Abstract
Impulsive aggression is a frequently occurring feature of psychopathic disorders and can be treated by pharmacotherapy. Controlled studies resulted in the use of the following agents for treatment of impulsive aggression (anti-impulsive aggression agents, AIAA) with the strongest evidence for efficacy: fluoxetine, phenytoin, divalproex/valproate, carbamazepine/oxycarbamazepine, and lithium. Starting from a risk-benefit analysis and research in the USA, this overview describes the selection and prescription of best possible AIAA suited for patients with psychopathic disorders. Positive and negative aspects for the selection and the prescription as well as possible mechanisms of action of the respective AIAAs are outlined. Furthermore, possibilities for the treatment of impulsive aggression in patients for whom an AIAA brought no improvement are explained.
| Translated title of the contribution | Pharmacotherapy of impulsive aggression in antisocial and psychopathic disorders |
|---|---|
| Original language | German |
| Pages (from-to) | 266-278 |
| Number of pages | 13 |
| Journal | Forensische Psychiatrie, Psychologie, Kriminologie |
| Volume | 12 |
| Issue number | 3 |
| DOIs | |
| State | Published - Aug 1 2018 |
Keywords
- Aggression, adult
- Anticonvulsants
- Impulse control
- Lithium
- Serotonin uptake inhibitors
- Violence
ASJC Scopus subject areas
- Applied Psychology
- Psychiatry and Mental health
- Law