Zinc aluminum layer double hydroxide ibuprofen PLLA nanocomposites: Synthesis, structure and characterization

Sriram Ambadapadi, Koffi Dagnon, Ali Shaito, Sunny M. Ogbomo, Maham Rahimi, Kytai Nguyen, Paul S. Braterman, Nandika Anne D'Souza

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The purpose of this research was to study the intercalation of the anions of Ibuprofen, non-steroidal anti-inflammatory drugs (NSAIDs), α-methyl-4-(2-methylpropyl)-benzene acetic acid into a layer double hydroxide (Zn-Al LDH) to form a new organic-inorganic hybrid intercalated material and the formation of nanocomposite with Poly (1-Lactic acid) (PLLA). The synthesis was achieved through two steps. The first step is the modification of layer double hydroxide with Ibuprofen anions. The second is the dispersion of the LDH into PLLA. The resulting organo-inorganic hybrid material was characterized by X-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC), and Tensile Test. X-ray diffraction evinces the presence of dispersion of LDH and intercalation.

Original languageEnglish (US)
Title of host publicationSociety of Plastics Engineers - 66th Annual Technical Conference of the Society of Plastics Engineers, Plastics Encounter at ANTEC 2008
Pages1654-1657
Number of pages4
Volume3
StatePublished - Sep 29 2008
Event66th Annual Technical Conference of the Society of Plastics Engineers, Plastics Encounter at ANTEC 2008 - Milwaukee, WI, United States
Duration: May 4 2008May 8 2008

Other

Other66th Annual Technical Conference of the Society of Plastics Engineers, Plastics Encounter at ANTEC 2008
CountryUnited States
CityMilwaukee, WI
Period5/4/085/8/08

Keywords

  • Ibuprofen
  • In vitro
  • Layer double hydroxide (LDH)
  • PLLA
  • Polymer clay nanocomposites

ASJC Scopus subject areas

  • Industrial and Manufacturing Engineering
  • Materials Chemistry
  • Polymers and Plastics

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