Zebrafish cell/neuron quantitation by modified circular hough transform

Tianming Liu, Jianfeng Lu, Jingxin Nie, Gang Li, Hui Yan, Jingyu Yang, Lei Guo, Weiming Xia, Stephen T.C. Wong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Microscopic imaging has become a critical step in the analysis of zebrafish phenotype, but tremendous amount of images generated from large number of embryos have become a bottleneck of data interpretation. The availability of an image informatics pipeline will be a significant step towards achieving reproducible quantitation of zebrafish phenotypes in scientific research and high-throughput screening. This paper presents an automated algorithm based on modified circular Hough transform for quantitation of zebrafish cells and neurons in microscopy imaging. Experimental results of three datasets are shown to demonstrate the performance of the algorithm. This algorithm has been integrated into our CBI Platform.

Original languageEnglish (US)
Title of host publication2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006
DOIs
StatePublished - 2006
Event2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006 - Bethesda, MD, United States
Duration: Jul 13 2006Jul 14 2006

Publication series

Name2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006

Other

Other2006 IEEE/NLM Life Science Systems and Applications Workshop, LiSA 2006
CountryUnited States
CityBethesda, MD
Period7/13/067/14/06

ASJC Scopus subject areas

  • Health(social science)
  • Assessment and Diagnosis
  • Medicine(all)
  • Health Information Management
  • Electrical and Electronic Engineering
  • Human-Computer Interaction
  • Computer Science Applications
  • Signal Processing

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