You're Too Old for That

Vinay A. Shah; Sandeep Randhawa; Thomas Mizen; Andrew G. Lee; Rod Foroozan

doi:10.1016/j.survophthal.2008.04.003

You're Too Old for That

Vinay A. Shah, Sandeep Randhawa, Thomas Mizen, Andrew G. Lee, Rod Foroozan

Research output: Contribution to journal › Comment/debate › peer-review

13 Scopus citations

Abstract

Leber hereditary optic neuropathy (LHON) produces a subacute and typically bilateral but sequential optic neuropathy. LHON is a mitochondrial disease and the most common mutations are at positions 11778, 14484 and 3460. LHON typically presents in young (age 20-40), healthy men but may occur in either sex and at any age. We report a case of LHON in a 72-year-old man and we emphasize the importance of testing for LHON in all cases of unexplained bilateral and sequential optic neuropathy with a ceco-central or central scotoma.

Original language	English (US)
Pages (from-to)	403-410
Number of pages	8
Journal	Survey of Ophthalmology
Volume	53
Issue number	4
DOIs	https://doi.org/10.1016/j.survophthal.2008.04.003
State	Published - 2008

Keywords

central scotoma
Leber hereditary optic neuropathy

ASJC Scopus subject areas

Ophthalmology

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10.1016/j.survophthal.2008.04.003

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title = "You're Too Old for That",

abstract = "Leber hereditary optic neuropathy (LHON) produces a subacute and typically bilateral but sequential optic neuropathy. LHON is a mitochondrial disease and the most common mutations are at positions 11778, 14484 and 3460. LHON typically presents in young (age 20-40), healthy men but may occur in either sex and at any age. We report a case of LHON in a 72-year-old man and we emphasize the importance of testing for LHON in all cases of unexplained bilateral and sequential optic neuropathy with a ceco-central or central scotoma.",

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T1 - You're Too Old for That

AU - Shah, Vinay A.

AU - Randhawa, Sandeep

AU - Mizen, Thomas

AU - Lee, Andrew G.

AU - Foroozan, Rod

PY - 2008

Y1 - 2008

N2 - Leber hereditary optic neuropathy (LHON) produces a subacute and typically bilateral but sequential optic neuropathy. LHON is a mitochondrial disease and the most common mutations are at positions 11778, 14484 and 3460. LHON typically presents in young (age 20-40), healthy men but may occur in either sex and at any age. We report a case of LHON in a 72-year-old man and we emphasize the importance of testing for LHON in all cases of unexplained bilateral and sequential optic neuropathy with a ceco-central or central scotoma.

AB - Leber hereditary optic neuropathy (LHON) produces a subacute and typically bilateral but sequential optic neuropathy. LHON is a mitochondrial disease and the most common mutations are at positions 11778, 14484 and 3460. LHON typically presents in young (age 20-40), healthy men but may occur in either sex and at any age. We report a case of LHON in a 72-year-old man and we emphasize the importance of testing for LHON in all cases of unexplained bilateral and sequential optic neuropathy with a ceco-central or central scotoma.

KW - central scotoma

KW - Leber hereditary optic neuropathy

UR - http://www.scopus.com/inward/record.url?scp=45249085471&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=45249085471&partnerID=8YFLogxK

U2 - 10.1016/j.survophthal.2008.04.003

DO - 10.1016/j.survophthal.2008.04.003

M3 - Comment/debate

C2 - 18572056

AN - SCOPUS:45249085471

SN - 0039-6257

VL - 53

SP - 403

EP - 410

JO - Survey of Ophthalmology

JF - Survey of Ophthalmology

IS - 4

ER -

You're Too Old for That

Abstract

Keywords

ASJC Scopus subject areas

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