You're Too Old for That

Vinay A. Shah, Sandeep Randhawa, Thomas Mizen, Andrew G. Lee, Rod Foroozan

Research output: Contribution to journalComment/debatepeer-review

13 Scopus citations


Leber hereditary optic neuropathy (LHON) produces a subacute and typically bilateral but sequential optic neuropathy. LHON is a mitochondrial disease and the most common mutations are at positions 11778, 14484 and 3460. LHON typically presents in young (age 20-40), healthy men but may occur in either sex and at any age. We report a case of LHON in a 72-year-old man and we emphasize the importance of testing for LHON in all cases of unexplained bilateral and sequential optic neuropathy with a ceco-central or central scotoma.

Original languageEnglish (US)
Pages (from-to)403-410
Number of pages8
JournalSurvey of Ophthalmology
Issue number4
StatePublished - 2008


  • central scotoma
  • Leber hereditary optic neuropathy

ASJC Scopus subject areas

  • Ophthalmology


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