YAP1 inhibitors and methods of treating a subject with a cancer that include administering a YAP1 inhibitor are disclosed. Also disclosed are methods for determining responsiveness to a YAP1 inhibitor in a subject, methods for diagnosing a tumor in a subject including determining the level of YAP1 expression, compositions that include YAP1 inhibitors, and methods of using those compositions.
|Original language||English (US)|
|Patent number||WO 2017/197104 Al|
|IPC||A61K 31/409 (2006.01) C07D 487/22 (2006.01)|
|State||Submitted - Nov 16 2017|