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Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma

Mari Kogiso, Lin Qi, Holly Lindsay, Yulun Huang, Xiumei Zhao, Zhigang Liu, Frank K. Braun, Yuchen Du, Huiyuan Zhang, Goeun Bae, Sibo Zhao, Sarah G. Injac, Mary Sobieski, David Brunell, Vidya Mehta, Diep Tran, Jeffrey Murray, Patricia A. Baxter, Xiao Jun Yuan, Jack M. SuAdekunle Adesina, Laszlo Perlaky, Murali Chintagumpala, D. Williams Parsons, Ching C. Lau, Clifford C. Stephan, Xinyan Lu, Xiao Nan Li

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Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology