Whole-body biodistribution and radiation dosimetry estimates for the pet dopamine transporter probe f-fecnt in non-human primates

Dnyanesh N. Tipre, Masahiro Fujita, Frederick T. Chin, Nicholas Seneca, Douglas Vines, Jeih San Liow, Victor W. Pike, Robert B. Innis

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

2β-Carbomethoxy-3-(4-chlorophenyl)-8-(2-[F]fluoroethyl)nortropane (F-FECNT) is a selective radioligand for the in vivo quantification of dopamine transporters by using positron emission tomography. The aim of the current study was to quantify the distribution of radioactivity in three rhesus monkeys after the injection of approximately 185 MBq (5 mCi) of F-FECNT.

Original languageEnglish (US)
Pages (from-to)737-742
Number of pages6
JournalNuclear medicine communications
Volume25
Issue number7
DOIs
StatePublished - Jul 2004

Keywords

  • Dopamine transporter
  • Dosimetry
  • F-FECNT
  • PET
  • Positron emission tomography
  • Whole-body biodistribution

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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