Whole-body biodistribution and radiation dosimetry estimates for the pet dopamine transporter probe f-fecnt in non-human primates

Dnyanesh N. Tipre; Masahiro Fujita; Frederick T. Chin; Nicholas Seneca; Douglas Vines; Jeih San Liow; Victor W. Pike; Robert B. Innis

doi:10.1097/01.mnm.0000133074.64669.60

Whole-body biodistribution and radiation dosimetry estimates for the pet dopamine transporter probe f-fecnt in non-human primates

Dnyanesh N. Tipre, Masahiro Fujita, Frederick T. Chin, Nicholas Seneca, Douglas Vines, Jeih San Liow, Victor W. Pike, Robert B. Innis

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

2β-Carbomethoxy-3-(4-chlorophenyl)-8-(2-[F]fluoroethyl)nortropane (F-FECNT) is a selective radioligand for the in vivo quantification of dopamine transporters by using positron emission tomography. The aim of the current study was to quantify the distribution of radioactivity in three rhesus monkeys after the injection of approximately 185 MBq (5 mCi) of F-FECNT.

Original language	English (US)
Pages (from-to)	737-742
Number of pages	6
Journal	Nuclear medicine communications
Volume	25
Issue number	7
DOIs	https://doi.org/10.1097/01.mnm.0000133074.64669.60
State	Published - Jul 2004

Keywords

Dopamine transporter
Dosimetry
F-FECNT
PET
Positron emission tomography
Whole-body biodistribution

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/01.mnm.0000133074.64669.60

Cite this

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title = "Whole-body biodistribution and radiation dosimetry estimates for the pet dopamine transporter probe f-fecnt in non-human primates",

abstract = "2β-Carbomethoxy-3-(4-chlorophenyl)-8-(2-[F]fluoroethyl)nortropane (F-FECNT) is a selective radioligand for the in vivo quantification of dopamine transporters by using positron emission tomography. The aim of the current study was to quantify the distribution of radioactivity in three rhesus monkeys after the injection of approximately 185 MBq (5 mCi) of F-FECNT.",

keywords = "Dopamine transporter, Dosimetry, F-FECNT, PET, Positron emission tomography, Whole-body biodistribution",

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T1 - Whole-body biodistribution and radiation dosimetry estimates for the pet dopamine transporter probe f-fecnt in non-human primates

AU - Tipre, Dnyanesh N.

AU - Fujita, Masahiro

AU - Chin, Frederick T.

AU - Seneca, Nicholas

AU - Vines, Douglas

AU - Liow, Jeih San

AU - Pike, Victor W.

AU - Innis, Robert B.

PY - 2004/7

Y1 - 2004/7

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AB - 2β-Carbomethoxy-3-(4-chlorophenyl)-8-(2-[F]fluoroethyl)nortropane (F-FECNT) is a selective radioligand for the in vivo quantification of dopamine transporters by using positron emission tomography. The aim of the current study was to quantify the distribution of radioactivity in three rhesus monkeys after the injection of approximately 185 MBq (5 mCi) of F-FECNT.

KW - Dopamine transporter

KW - Dosimetry

KW - F-FECNT

KW - PET

KW - Positron emission tomography

KW - Whole-body biodistribution

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Whole-body biodistribution and radiation dosimetry estimates for the pet dopamine transporter probe f-fecnt in non-human primates

Abstract

Keywords

ASJC Scopus subject areas

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