Whipple disease of the central nervous system: An unusual occurrence in association with acquired immune deficiency syndrome

Bharat Guthikonda; Emilie Rouah; Bhuvanaswari Krishnan; Suzanne Zein-Eldin Powell; J. Clay Goodman; Shankar P. Gopinath; Richard K. Simpson

doi:10.3171/2009.6.JNS0935

Whipple disease of the central nervous system: An unusual occurrence in association with acquired immune deficiency syndrome

Bharat Guthikonda, Emilie Rouah, Bhuvanaswari Krishnan, Suzanne Zein-Eldin Powell, J. Clay Goodman, Shankar P. Gopinath, Richard K. Simpson

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.

Original language	English (US)
Pages (from-to)	983-989
Number of pages	7
Journal	Journal of Neurosurgery
Volume	112
Issue number	5
DOIs	https://doi.org/10.3171/2009.6.JNS0935
State	Published - May 2010

Keywords

Acquired immune deficiency syndrome
Central nervous system infection
Electron microscopy
Stereotactic biopsy
Whipple disease

ASJC Scopus subject areas

Clinical Neurology
Surgery

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10.3171/2009.6.JNS0935

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title = "Whipple disease of the central nervous system: An unusual occurrence in association with acquired immune deficiency syndrome",

abstract = "Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20\% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.",

keywords = "Acquired immune deficiency syndrome, Central nervous system infection, Electron microscopy, Stereotactic biopsy, Whipple disease",

author = "Bharat Guthikonda and Emilie Rouah and Bhuvanaswari Krishnan and Powell, \{Suzanne Zein-Eldin\} and Goodman, \{J. Clay\} and Gopinath, \{Shankar P.\} and Simpson, \{Richard K.\}",

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T2 - An unusual occurrence in association with acquired immune deficiency syndrome

AU - Guthikonda, Bharat

AU - Rouah, Emilie

AU - Krishnan, Bhuvanaswari

AU - Powell, Suzanne Zein-Eldin

AU - Goodman, J. Clay

AU - Gopinath, Shankar P.

AU - Simpson, Richard K.

PY - 2010/5

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N2 - Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.

AB - Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.

KW - Acquired immune deficiency syndrome

KW - Central nervous system infection

KW - Electron microscopy

KW - Stereotactic biopsy

KW - Whipple disease

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JO - Journal of Neurosurgery

JF - Journal of Neurosurgery

IS - 5

ER -

Whipple disease of the central nervous system: An unusual occurrence in association with acquired immune deficiency syndrome

Abstract

Keywords

ASJC Scopus subject areas

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