TY - JOUR
T1 - Whipple disease of the central nervous system
T2 - An unusual occurrence in association with acquired immune deficiency syndrome
AU - Guthikonda, Bharat
AU - Rouah, Emilie
AU - Krishnan, Bhuvanaswari
AU - Powell, Suzanne Zein-Eldin
AU - Goodman, J. Clay
AU - Gopinath, Shankar P.
AU - Simpson, Richard K.
PY - 2010/5
Y1 - 2010/5
N2 - Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.
AB - Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.
KW - Acquired immune deficiency syndrome
KW - Central nervous system infection
KW - Electron microscopy
KW - Stereotactic biopsy
KW - Whipple disease
UR - http://www.scopus.com/inward/record.url?scp=77952046004&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952046004&partnerID=8YFLogxK
U2 - 10.3171/2009.6.JNS0935
DO - 10.3171/2009.6.JNS0935
M3 - Article
C2 - 19612977
AN - SCOPUS:77952046004
SN - 0022-3085
VL - 112
SP - 983
EP - 989
JO - Journal of Neurosurgery
JF - Journal of Neurosurgery
IS - 5
ER -