Whipple disease of the central nervous system: An unusual occurrence in association with acquired immune deficiency syndrome

Bharat Guthikonda, Emilie Rouah, Bhuvanaswari Krishnan, Suzanne Zein-Eldin Powell, J. Clay Goodman, Shankar P. Gopinath, Richard K. Simpson

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Whipple disease is a multisystem infectious disease caused by Tropheryma whippleii. It commonly affects the CNS and produces neurological symptoms in 10-20% of cases. Central nervous system Whipple disease occurring in patients with AIDS is extremely rare. The authors present a case of a newly diagnosed AIDS patient in whom intracranial Whipple disease was diagnosed by stereotactic brain biopsy.

Original languageEnglish (US)
Pages (from-to)983-989
Number of pages7
JournalJournal of Neurosurgery
Volume112
Issue number5
DOIs
StatePublished - May 2010

Keywords

  • Acquired immune deficiency syndrome
  • Central nervous system infection
  • Electron microscopy
  • Stereotactic biopsy
  • Whipple disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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