Wettability of Mg-HA/Chitosan-based membrane surfaces: blood vs. autologous platelet liquid (APL)

F. Lorusso, C. Mortellaro, A. Greco Lucchina, G. Falisi, C. Bugea, A. Tampieri, M. S. Di Carmine, A. Scarano

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: The physical and physical chemistry is able to influence the interaction of the scaffolds and bone substitutes with the body fluid and blood. The aim of the present investigation was to evaluate the wettability properties of an Mg-HA Chitosan-based Gel with blood vs. autologous platelet gel.

MATERIALS AND METHODS: A total of 6 study groups were evaluated according to the Mg-HA Chitosan-based Gel thickness (1, 2 and 3 mm) and the fluids (blood vs. autologous platelet gel). The biomaterial wettability was conducted through the sessile drop technique.

RESULTS: The study findings showed a significant difference in contact angle between the APL and blood groups (p<0.05). The MG-Ha Chitosan-based membrane thicknesses seem to produce no significant effects on contact angles measurement for all groups (p>0.05).

CONCLUSIONS: In the present investigation, a similar MG/Ha gel membranes wettability was reported between APL and blood groups. In addition, a high hydrophilicity of MG/Ha gel membranes was reported with a potential advantage in terms of a more effective osteogenic capability in the clinical practice.

Original languageEnglish (US)
Pages (from-to)153-161
Number of pages9
JournalEuropean Review for Medical and Pharmacological Sciences
Volume27
Issue number3 Suppl
DOIs
StatePublished - 2023

Keywords

  • Blood platelets
  • Dental implant
  • Osseointegrated dental implantation
  • Platelet derived growth factor
  • Wettability
  • Biocompatible Materials/chemistry
  • Blood Platelets
  • Chitosan
  • Osteogenesis

ASJC Scopus subject areas

  • Pharmacology (medical)

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