Weaning from Mechanical Ventilator in a Long-term Acute Care Hospital: A Retrospective Analysis

Salim Surani, Munish Sharma, Kevin Middagh, Hector Bernal, Joseph Varon, Iqbal Ratnani, Humayun Anjum, Alamgir Khan

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background: Prolonged Mechanical Ventilation (PMV) is associated with a higher cost of care and increased morbidity and mortality. Patients requiring PMV are referred mostly to Long-Term Acute Care (LTAC) facilities. Objective: To determine if protocol-driven weaning from mechanical ventilator by Respiratory Therapist (RT) would result in quicker weaning from mechanical ventilation, cost-effectiveness, and decreased mortality. Methods: A retrospective case-control study was conducted that utilized protocol-driven ventilator weaning by respiratory therapist (RT) as a part of the Respiratory Disease Certification Program (RDCP). Results: 51 patients on mechanical ventilation before initiation of protocol-based ventilator weaning formed the control group. 111 patients on mechanical ventilation after implementation of the protocol formed the study group. Time to wean from the mechanical ventilation before the implementation of protocol-driven weaning by RT was 16.76 +/-18.91 days, while that after the implementation of protocol was 7.67 +/-6.58 days (p < 0.0001). Mortality proportion in patients after implementation of protocol-based ventilator weaning was 0.21 as compared to 0.37 in the control group (p=0.0153). The daily cost of patient care for the LTAC while on mechanical ventilation was $2200/day per patient while it was $ 1400/day per patient while not on mechanical ventilation leading to significant cost savings. Conclusion: Protocol-driven liberation from mechanical ventilation in LTAC by RT can significantly decrease the duration of a mechanical ventilator, leading to decreased mortality and cost savings.

Original languageEnglish (US)
Pages (from-to)62-66
Number of pages5
JournalOpen Respiratory Medicine Journal
Issue number1
StatePublished - 2020


  • Difficult weaning
  • Liberation from mechanical ventilation
  • Long term acute care
  • Prolonged mechanical ventilation
  • Respiratory therapist in weaning
  • Ventilator weaning

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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