Vision loss 2 weeks after uneventful optic nerve sheath fenestration surgery may be attributed to retinal reperfusion injury

Purpose: The purpose of this study was to report a rare case of retinal reperfusion injury after optic nerve sheath fenestration surgery. Patients and Methods: Single patient case report. Results: A 58-year-old African American woman presented with severe visual loss in the right eye 2 weeks after optic nerve sheath fenestration surgery. Retinal examination at presentation showed severe arterial narrowing and the appearance of new intraretinal hemorrhages. Fluorescein angiography demonstrated delayed venous filling. Conclusion: Severe visual loss after optic nerve sheath fenestration procedure is uncommon. This case may represent the first reported case of reperfusion injury in human eyes.