@article{2a4220e9023c4f4b909187bdf8d3fd97,
title = "Virus detection using nanoelectromechanical devices",
abstract = "The binding events of the baculovirus was measured using arrays of chemically functionalized, surface micromachined polycrystalline silicon cantilevers. The 0.5 μm×6 μm cantilevers have mass sensitivities on the order of 10 -19 g/Hz, that enables to detect an immobilized AcV1 antibody monolayer corresponsing to mass of about 3×10 -15 g. The resonant frequency shift was observed from the adsorbed mass of the virus particles distinguished solutions of virus concentrations and varies between 10 5 and 10 7 pfu/ml. The mass of single-virus particles bound to the cantilever can also be detected using cantilevers.",
author = "B. Ilic and Y. Yang and Craighead, {H. G.}",
note = "Funding Information: The authors would like to thank Professor Michael Shuler (Department of Chemical and Biomolecular Engineering, Cornell University) for providing facilities for insect cell culture and virus amplification. Additionally, hybridoma cell line producing AcV1 monoclonal antibody against the gp64 coat protein of Autographa californica nuclear polyhedrosis virus (AcNPV) was generously provided by Professor Gary Blissard (Boyce Thompson Institute for Plant Research, Ithaca, NY). Furthermore, the authors would like to thank the staff at the Cornell NanoScale Facility for helpful discussion and generous aid in fabrication. This work was supported in part by DARPA, NSF through the Nanobiotechnology Center, and New York State.",
year = "2004",
month = sep,
day = "27",
doi = "10.1063/1.1794378",
language = "English (US)",
volume = "85",
pages = "2604--2606",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics Publising LLC",
number = "13",
}