VIM deep brain stimulation does not improve pre-existing restless legs syndrome in patients with essential tremor

William Ondo

doi:10.1016/j.parkreldis.2004.10.015

VIM deep brain stimulation does not improve pre-existing restless legs syndrome in patients with essential tremor

William Ondo

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

The neuroanatomic substrate for restless legs syndrome (RLS) is not known. We implanted deep brain stimulators into the ventralis intermedius nucleus (VIM) of the thalamus in nine subjects for essential tremor (ET) whom all concurrently had RLS. Although the VIM DBS improved tremor, none of the subjects felt there was any meaningful effect on their RLS symptoms. The VIM thalamus, which is involved in ET and Parkinson's disease, does not seem to be primarily involved in RLS.

Original language	English (US)
Pages (from-to)	113-114
Number of pages	2
Journal	Parkinsonism and Related Disorders
Volume	12
Issue number	2
DOIs	https://doi.org/10.1016/j.parkreldis.2004.10.015
State	Published - Mar 2006

Keywords

Deep brain stimulation
Essential tremor
Restless legs syndrome
Thalamus

ASJC Scopus subject areas

Neurology
Geriatrics and Gerontology
Clinical Neurology

Access to Document

10.1016/j.parkreldis.2004.10.015

Cite this

@article{dfcaae9c464442429ee947ed582b1d7b,

title = "VIM deep brain stimulation does not improve pre-existing restless legs syndrome in patients with essential tremor",

abstract = "The neuroanatomic substrate for restless legs syndrome (RLS) is not known. We implanted deep brain stimulators into the ventralis intermedius nucleus (VIM) of the thalamus in nine subjects for essential tremor (ET) whom all concurrently had RLS. Although the VIM DBS improved tremor, none of the subjects felt there was any meaningful effect on their RLS symptoms. The VIM thalamus, which is involved in ET and Parkinson's disease, does not seem to be primarily involved in RLS.",

keywords = "Deep brain stimulation, Essential tremor, Restless legs syndrome, Thalamus",

author = "William Ondo",

year = "2006",

month = mar,

doi = "10.1016/j.parkreldis.2004.10.015",

language = "English (US)",

volume = "12",

pages = "113--114",

journal = "Parkinsonism and Related Disorders",

issn = "1353-8020",

publisher = "Elsevier Ltd",

number = "2",

}

TY - JOUR

T1 - VIM deep brain stimulation does not improve pre-existing restless legs syndrome in patients with essential tremor

AU - Ondo, William

PY - 2006/3

Y1 - 2006/3

N2 - The neuroanatomic substrate for restless legs syndrome (RLS) is not known. We implanted deep brain stimulators into the ventralis intermedius nucleus (VIM) of the thalamus in nine subjects for essential tremor (ET) whom all concurrently had RLS. Although the VIM DBS improved tremor, none of the subjects felt there was any meaningful effect on their RLS symptoms. The VIM thalamus, which is involved in ET and Parkinson's disease, does not seem to be primarily involved in RLS.

AB - The neuroanatomic substrate for restless legs syndrome (RLS) is not known. We implanted deep brain stimulators into the ventralis intermedius nucleus (VIM) of the thalamus in nine subjects for essential tremor (ET) whom all concurrently had RLS. Although the VIM DBS improved tremor, none of the subjects felt there was any meaningful effect on their RLS symptoms. The VIM thalamus, which is involved in ET and Parkinson's disease, does not seem to be primarily involved in RLS.

KW - Deep brain stimulation

KW - Essential tremor

KW - Restless legs syndrome

KW - Thalamus

UR - http://www.scopus.com/inward/record.url?scp=32544433150&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=32544433150&partnerID=8YFLogxK

U2 - 10.1016/j.parkreldis.2004.10.015

DO - 10.1016/j.parkreldis.2004.10.015

M3 - Article

C2 - 16446110

AN - SCOPUS:32544433150

SN - 1353-8020

VL - 12

SP - 113

EP - 114

JO - Parkinsonism and Related Disorders

JF - Parkinsonism and Related Disorders

IS - 2

ER -

VIM deep brain stimulation does not improve pre-existing restless legs syndrome in patients with essential tremor

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this