Vesicular Carriers for Enhanced delivery through the skin

Elka Touitou, Biana Godin

Research output: Chapter in Book/Report/Conference proceedingChapter

12 Scopus citations

Abstract

Dermal and transdermal delivery requires efficient penetration of compounds through the skin barrier, the bilayer domains of intercellular lipid matrices, and keratin bundles in the stratum corneum (SC). Lipid vesicular systems are a recognized mode of enhanced delivery of drugs into and through the skin. However, it is noteworthy that not every lipid vesicular system has the adequate characteristics to enhance skin membrane permeation. Specially designed lipid vesicles in contrast to classic liposomal compositions could achieve this goal. This chapter describes the structure, main physicochemical characteristics, and mechanism of action of prominent vesicular carriers in this field and reviews reported data on their enhanced delivery performance.

Original languageEnglish (US)
Title of host publicationEnhancement in Drug Delivery
PublisherCRC Press
Pages255-278
Number of pages24
ISBN (Electronic)9781420004816
ISBN (Print)9780849332036
StatePublished - Jan 1 2006

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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