Verrucous carcinoma of the esophagus: A potential diagnostic dilemma

Kabir Ahmed, Gary Timmerman, Robert Meyer, Tara Miller, Miroslaw Mazurczak, Kimberlee Tams, Muslim Atiq

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Verrucous carcinoma of the esophagus is a rare variant of squamous cell carcinoma associated with human papillomavirus. We report the case of a 58-year-old female who presented with ongoing symptoms of dysphagia. On previous endoscopies she had been noted to have a large polyp-like mass involving the esophagus, with negative biopsies for malignancy. Repeat endoscopy with concurrent endoscopic ultrasound showed a large semi-pedunculated polyp in the distal esophagus and a hypoechoic, irregular mass involving the gastroesophageal junction with esophageal thickening. Deep layer biopsies showed pseudoepitheliomatous hyperplasia with immunohistochemical staining positive for human papillomavirus. The patient was subsequently treated with chemo-radiation followed by esophagectomy.

Original languageEnglish (US)
Pages (from-to)498-502
Number of pages5
JournalCase Reports in Gastroenterology
Volume7
Issue number3
DOIs
StatePublished - 2013

Keywords

  • Esophagus
  • Human papillomavirus
  • Verrucous carcinoma

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Verrucous carcinoma of the esophagus: A potential diagnostic dilemma'. Together they form a unique fingerprint.

Cite this