Verification of proton density change in spinal cord fMRI

Man Cheuk Ng, Kelvin Wong, Geng Li, Qi Yuan Ma, Edward S. Yang, Yang Hu, Keith D.K. Luk

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

The existence of a second contrast mechanism, Signal Enhancement due to Extravascular Proton, other than the Blood Oxygenation Level Dependent, was reported in functional magnetic resonance imaging studies of the brain and spinal cord. This mechanism was suggested to be due to the task-induced increase of extravascular proton density. In the current study, we are trying to show the existence of proton density change in the spinal cords by using low field proton density weighted magnetic resonance imaging. In the experiment, motor task with a block design paradigm was used to give stimulation to normal subjects. Activation correlating with neural anatomy was detected. This paper verifies that there is proton density change in the spinal cord during functional activation.

Original languageEnglish (US)
Title of host publicationProceedings of the Fourth IASTED International Conference on Visualization, Imaging, and Image Processing
EditorsJ.J. Villanueva
Pages926-930
Number of pages5
StatePublished - Dec 1 2004
EventProceedings of the Fourth IASTED International Conference on Visualization, Imaging, and Image Processing - Marbella, Spain
Duration: Sep 6 2004Sep 8 2004

Other

OtherProceedings of the Fourth IASTED International Conference on Visualization, Imaging, and Image Processing
CountrySpain
CityMarbella
Period9/6/049/8/04

Keywords

  • BOLD
  • FMRI
  • MRI
  • Proton density
  • SEEP
  • Spinal cord

ASJC Scopus subject areas

  • Engineering(all)

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