TY - JOUR
T1 - Vasculink iPhone Application and Risk Prediction Model for Groin Complication in Vascular Surgery
AU - Livingston, Kenneth A.
AU - Koh, Ezra
AU - Adlouni, Mu'ath
AU - Hassan, Adel
AU - Gan, Weicheng
AU - MS, Yijun zhang
AU - Falohun, Tokunbo
AU - Peden, Eric K.
AU - Rahimi, Maham
N1 - Funding Information:
Funding: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Declaration of Interests: Kenneth A. Livingston, B.S.: None. Ezra Koh, M.D.: None. Mu'ath Adlouni, B.S: None. Adel Hassan, B.S.: None. Weicheng Gan, M.S.: None. Yijun zhang, M.S.: None. Tokunbo Falohun, M.S.: None. Eric K. Peden, M.D.: Consulting Fees (e.g., advisory boards), Other Financial or Material Support for the following: Artegraft, Inc; Humacyte, Inc.; Laminate Medical Technologies, LTD; Merck Sharpe & Dohme Corp; Merit; TVA Medical/Bard/BD Medical. VenoStent: Salary and Contracted Research. Maham Rahimi, M.D., Ph.D.: None.
Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2022/9
Y1 - 2022/9
N2 - Background: Postoperative groin complication is a common cause of morbidity in vascular surgery. Prophylactic wound adjuncts addressing this issue have been shown to reduce complications in high-risk patients, but their widespread implementation is limited by their high cost. This study introduces a risk prediction model for patients at a high risk for groin complication which can be accessed through the iPhone application, Vasculink. Methods: A literature search identified risk prediction models for groin complication in vascular surgery. Odds ratios of risk factors that were present in at least 2 published models were calculated with a pooled effect size. The weighted risk for each factor was used to create our model and a cutoff point defining high risk patients was chosen. The initial model was assessed and validated using a split-sample methodology on a cohort identified via a retrospective chart review of all patients undergoing open vascular surgery at our institution between 2017 and 2020. Model performance was assessed using the C-statistic. Results: Risk factors included in our model were female gender, body mass index ≥28 kg/m2, ever-smoker, reoperation, use of prosthetic, emergency, and end-stage renal disease. Of 216 patients, 131 were at a high risk. The overall groin complication rate was 43%, and specific complication rates were 27% infection, 14.8% seroma, and 6.9% hematoma. Our model's sensitivity and specificity were 92.47% and 60.98%, respectively. The C-statistic is 0.768. Conclusions: By using risk factors identified in the literature we have been able to establish a highly sensitive risk prediction model for groin complication following open vascular surgery. By incorporating our model into an iPhone application, Vasculink, we hope to facilitate preoperative decision making regarding the use of prophylactic wound adjuncts.
AB - Background: Postoperative groin complication is a common cause of morbidity in vascular surgery. Prophylactic wound adjuncts addressing this issue have been shown to reduce complications in high-risk patients, but their widespread implementation is limited by their high cost. This study introduces a risk prediction model for patients at a high risk for groin complication which can be accessed through the iPhone application, Vasculink. Methods: A literature search identified risk prediction models for groin complication in vascular surgery. Odds ratios of risk factors that were present in at least 2 published models were calculated with a pooled effect size. The weighted risk for each factor was used to create our model and a cutoff point defining high risk patients was chosen. The initial model was assessed and validated using a split-sample methodology on a cohort identified via a retrospective chart review of all patients undergoing open vascular surgery at our institution between 2017 and 2020. Model performance was assessed using the C-statistic. Results: Risk factors included in our model were female gender, body mass index ≥28 kg/m2, ever-smoker, reoperation, use of prosthetic, emergency, and end-stage renal disease. Of 216 patients, 131 were at a high risk. The overall groin complication rate was 43%, and specific complication rates were 27% infection, 14.8% seroma, and 6.9% hematoma. Our model's sensitivity and specificity were 92.47% and 60.98%, respectively. The C-statistic is 0.768. Conclusions: By using risk factors identified in the literature we have been able to establish a highly sensitive risk prediction model for groin complication following open vascular surgery. By incorporating our model into an iPhone application, Vasculink, we hope to facilitate preoperative decision making regarding the use of prophylactic wound adjuncts.
KW - Female
KW - Groin/blood supply
KW - Humans
KW - Male
KW - Postoperative Complications/etiology
KW - Retrospective Studies
KW - Risk Factors
KW - Surgical Wound Infection/etiology
KW - Treatment Outcome
KW - Vascular Surgical Procedures/adverse effects
UR - http://www.scopus.com/inward/record.url?scp=85132673217&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85132673217&partnerID=8YFLogxK
U2 - 10.1016/j.avsg.2022.03.039
DO - 10.1016/j.avsg.2022.03.039
M3 - Article
C2 - 35398195
AN - SCOPUS:85132673217
SN - 0890-5096
VL - 85
SP - 237
EP - 245
JO - Annals of Vascular Surgery
JF - Annals of Vascular Surgery
ER -