Vagal Nerve Simulation

Vivek Mehta, Daniel Kramer, Jonathan Russin, Charles Liu, Arun Amar

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Vagus nerve stimulation (VNS) is a safe and reliable treatment adjunct for patients with medically intractable epilepsy. It is both a preventive and an abortive form of therapy, effective against both partial and generalized seizures in adults and children. VNS also has a number of serendipitous effects on mood, memory, and attention, and has been approved for the treatment of refractory depression. Its principal limitations are its unknown mechanism of action, the low likelihood of complete cure, and the inability to predict which patients will derive substantial benefit. This chapter reviews the theoretical rationale, practical background, and clinical applications of VNS therapy.

Original languageEnglish (US)
Title of host publicationNeuromodulation
Subtitle of host publicationComprehensive Textbook of Principles, Technologies, and Therapies, Second Edition: Volume 1-3
PublisherElsevier
Pages999-1009
Number of pages11
Volume3
ISBN (Electronic)9780128053539
ISBN (Print)9780128093023
DOIs
StatePublished - Jan 1 2018

Keywords

  • Depression
  • Epilepsy
  • Neurostimulation
  • Seizure
  • Vagus nerve stimulation

ASJC Scopus subject areas

  • Neuroscience(all)

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