Vaccines and cardiovascular outcomes: lessons learned from influenza epidemics

Siva H. Yedlapati, Anuradha Mendu, Venkat R. Tummala, Sowmith S. Maganti, Khurram Nasir, Safi U. Khan

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Cardiovascular disease (CVD) is the leading cause of death in the world and is largely preventable. An increasing amount of evidence suggests that annual influenza vaccination reduces CVD-related morbidity and mortality. Despite various clinical guidelines recommending annual influenza vaccination for the general population for influenza-like illness risk reduction, with a particular emphasis on people with CVD, vaccination rates fall consistently below the goal established by the World Health Organization. This review outlines the importance of influenza vaccination, mechanisms of cardiovascular events in influenza, summarizing the available literature on the effects of influenza vaccine in CVD and the benefits of influenza vaccine during the COVID-19 pandemic.

Original languageEnglish (US)
Pages (from-to)A17-A24
JournalEuropean Heart Journal, Supplement
Issue numberSuppl A
StatePublished - Feb 1 2023


  • Cardiovascular disease
  • Influenza vaccine
  • Prevention

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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