Utilizing TH9 cells as a novel therapeutic strategy for malignancies

Yong Lu, Qing Yi

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

TH9 cells join the ever-growing list of CD4+ T helper subsets and primarily mediate anti-parasite immune responses. We have recently demonstrated that tumor-specific TH9 cells induce a CCL20-CCR6-dependent regulation of DCs while stimulating CD8+ T cell-mediated antitumor immunity. These findings offer a novel immunotherapeutic strategy against cancer.

Original languageEnglish (US)
Article numbere23084
JournalOncoImmunology
Volume2
Issue number3
DOIs
StatePublished - Mar 2013

Keywords

  • Ccl20
  • DCs
  • Melanoma
  • TCLs
  • Th9 cell

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology

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