Utility of Repeating Blood Cultures in Candidemia: Insights From 2 Large Clinical Data Repositories

Hisato Yoshida; Max W. Adelman; Francis Ifiora; María Alejandra Pérez; Marilyn Niravath; Hitoshi Yoshimura; Stephen L. Jones; Cesar A. Arias; Masayuki Nigo

doi:10.1093/cid/ciag216

Utility of Repeating Blood Cultures in Candidemia: Insights From 2 Large Clinical Data Repositories

Hisato Yoshida, Max W. Adelman, Francis Ifiora, María Alejandra Pérez, Marilyn Niravath, Hitoshi Yoshimura, Stephen L. Jones, Cesar A. Arias, Masayuki Nigo

Research output: Contribution to journal › Article › peer-review

Abstract

We evaluated utility of repeating blood culture for candidemia using 2 electronic health record datasets. Among 1386 candidemia episodes, repeated blood culture detected 23% of episodes at Houston Methodist Hospital and 45% in Medical Information Mart for Intensive Care IV after the initial negative cultures. These findings support repeating blood cultures when candidemia is highly suspected.

Original language	English (US)
Pages (from-to)	e105-e108
Journal	Clinical Infectious Diseases
Volume	83
Issue number	1
DOIs	https://doi.org/10.1093/cid/ciag216
State	Published - Jul 15 2026

Keywords

blood culture
candidemia
Candidemia/diagnosis
Candida/isolation & purification
Humans
Blood Culture/methods
Electronic Health Records

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

Divisions

Pulmonary, Critical Care and Sleep Medicine
Infectious Disease

Access to Document

10.1093/cid/ciag216

Cite this

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title = "Utility of Repeating Blood Cultures in Candidemia: Insights From 2 Large Clinical Data Repositories",

abstract = "We evaluated utility of repeating blood culture for candidemia using 2 electronic health record datasets. Among 1386 candidemia episodes, repeated blood culture detected 23\% of episodes at Houston Methodist Hospital and 45\% in Medical Information Mart for Intensive Care IV after the initial negative cultures. These findings support repeating blood cultures when candidemia is highly suspected.",

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doi = "10.1093/cid/ciag216",

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AU - Yoshida, Hisato

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AU - Ifiora, Francis

AU - Pérez, María Alejandra

AU - Niravath, Marilyn

AU - Yoshimura, Hitoshi

AU - Jones, Stephen L.

AU - Arias, Cesar A.

AU - Nigo, Masayuki

N1 - © The Author(s) 2026. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

PY - 2026/7/15

Y1 - 2026/7/15

N2 - We evaluated utility of repeating blood culture for candidemia using 2 electronic health record datasets. Among 1386 candidemia episodes, repeated blood culture detected 23% of episodes at Houston Methodist Hospital and 45% in Medical Information Mart for Intensive Care IV after the initial negative cultures. These findings support repeating blood cultures when candidemia is highly suspected.

AB - We evaluated utility of repeating blood culture for candidemia using 2 electronic health record datasets. Among 1386 candidemia episodes, repeated blood culture detected 23% of episodes at Houston Methodist Hospital and 45% in Medical Information Mart for Intensive Care IV after the initial negative cultures. These findings support repeating blood cultures when candidemia is highly suspected.

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KW - Candidemia/diagnosis

KW - Candida/isolation & purification

KW - Humans

KW - Blood Culture/methods

KW - Electronic Health Records

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Utility of Repeating Blood Cultures in Candidemia: Insights From 2 Large Clinical Data Repositories

Abstract

Keywords

ASJC Scopus subject areas

Divisions

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