Use of T2MR in invasive candidiasis with and without candidemia

Ioannis M. Zacharioudakis, Fainareti N. Zervou, Eleftherios Mylonakis

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


The mortality associated with invasive candidiasis remains unacceptably high. The T2 magnetic resonance (T2MR) assay is a novel US FDA-Approved molecular diagnostic assay for the diagnosis of candidemia that can rapidly detect the five most commonly isolated Candida spp. In clinical trials, T2MR has exhibited good clinical sensitivity and specificity. Potential benefits from the adoption of T2MR technology in the diagnostic and therapeutic algorithms for invasive candidiasis can arise from timely diagnosis of disease, increased case detection, tailored therapy and decrease in empiric antifungal treatment. As everyday clinical experience with the assay is evolving, we discuss the utility of T2MR in invasive candidiasis with and without candidemia based on the currently available evidence regarding its performance.

Original languageEnglish (US)
Pages (from-to)1165-1173
Number of pages9
JournalFuture Microbiology
Issue number10
StatePublished - Aug 2018


  • T2Candida
  • T2MR
  • abdominal candidiasis
  • candidemia
  • chronic disseminated candidiasis
  • invasive candidiasis

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)


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