Use of pipeline flow diverting stents for wide neck intracranial aneurysms: A retrospective institutional review

Abhishek Agarwal; Sankalp Gokhale; Jagan Gupta; Roman Raju; Shahid Nimjee; Tony Smith; Gavin W Britz

doi:10.4103/1793-5482.131057

Use of pipeline flow diverting stents for wide neck intracranial aneurysms: A retrospective institutional review

Abhishek Agarwal, Sankalp Gokhale, Jagan Gupta, Roman Raju, Shahid Nimjee, Tony Smith, Gavin W Britz

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Intracranial aneurysms (ICA) if inadequately treated may result in serious morbidity and mortality. Wide-neck; large/giant, fusiform, and dissecting aneurysms are not well treated using the conventional coil embolization technique. Recent advance in endovascular treatment and technology has introduced flow diverter devices including pipeline embolization devices (PED) and Silk stents that have been shown to be more effective in treating these more complicated aneurysms. Flow Diverter devices offer a more physiologic approach to ICA treatment.

METHODS: We conducted a retrospective chart review of 23 adult patients who underwent aneurysm treatment utilizing the pipeline stent at Duke University Medical Center from July 2011 to March 2013.

RESULTS: Majority of patients (19, 82.7%) showed angiographic evidence of complete obliteration of aneurysm at 6 months follow-up, with sustained clinical improvement on modified Rankin scale score. All of the patients tolerated the procedure well with no intra-operative hemorrhage or intra-operative thromboembolic complications.

CONCLUSIONS: Our experience shows that use of PED offers a safe and effective strategy for treatment of complex ICA. Larger prospective studies are needed to confirm these observations.

Original language	English (US)
Pages (from-to)	3-6
Number of pages	4
Journal	Asian Journal of Neurosurgery
Volume	9
Issue number	1
DOIs	https://doi.org/10.4103/1793-5482.131057
State	Published - Jan 2014

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title = "Use of pipeline flow diverting stents for wide neck intracranial aneurysms: A retrospective institutional review",

abstract = "BACKGROUND: Intracranial aneurysms (ICA) if inadequately treated may result in serious morbidity and mortality. Wide-neck; large/giant, fusiform, and dissecting aneurysms are not well treated using the conventional coil embolization technique. Recent advance in endovascular treatment and technology has introduced flow diverter devices including pipeline embolization devices (PED) and Silk stents that have been shown to be more effective in treating these more complicated aneurysms. Flow Diverter devices offer a more physiologic approach to ICA treatment.METHODS: We conducted a retrospective chart review of 23 adult patients who underwent aneurysm treatment utilizing the pipeline stent at Duke University Medical Center from July 2011 to March 2013.RESULTS: Majority of patients (19, 82.7%) showed angiographic evidence of complete obliteration of aneurysm at 6 months follow-up, with sustained clinical improvement on modified Rankin scale score. All of the patients tolerated the procedure well with no intra-operative hemorrhage or intra-operative thromboembolic complications.CONCLUSIONS: Our experience shows that use of PED offers a safe and effective strategy for treatment of complex ICA. Larger prospective studies are needed to confirm these observations.",

author = "Abhishek Agarwal and Sankalp Gokhale and Jagan Gupta and Roman Raju and Shahid Nimjee and Tony Smith and Britz, {Gavin W}",

year = "2014",

month = jan,

doi = "10.4103/1793-5482.131057",

language = "English (US)",

volume = "9",

pages = "3--6",

journal = "Asian Journal of Neurosurgery",

issn = "1793-5482",

number = "1",

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T1 - Use of pipeline flow diverting stents for wide neck intracranial aneurysms

T2 - A retrospective institutional review

AU - Agarwal, Abhishek

AU - Gokhale, Sankalp

AU - Gupta, Jagan

AU - Raju, Roman

AU - Nimjee, Shahid

AU - Smith, Tony

AU - Britz, Gavin W

PY - 2014/1

Y1 - 2014/1

N2 - BACKGROUND: Intracranial aneurysms (ICA) if inadequately treated may result in serious morbidity and mortality. Wide-neck; large/giant, fusiform, and dissecting aneurysms are not well treated using the conventional coil embolization technique. Recent advance in endovascular treatment and technology has introduced flow diverter devices including pipeline embolization devices (PED) and Silk stents that have been shown to be more effective in treating these more complicated aneurysms. Flow Diverter devices offer a more physiologic approach to ICA treatment.METHODS: We conducted a retrospective chart review of 23 adult patients who underwent aneurysm treatment utilizing the pipeline stent at Duke University Medical Center from July 2011 to March 2013.RESULTS: Majority of patients (19, 82.7%) showed angiographic evidence of complete obliteration of aneurysm at 6 months follow-up, with sustained clinical improvement on modified Rankin scale score. All of the patients tolerated the procedure well with no intra-operative hemorrhage or intra-operative thromboembolic complications.CONCLUSIONS: Our experience shows that use of PED offers a safe and effective strategy for treatment of complex ICA. Larger prospective studies are needed to confirm these observations.

AB - BACKGROUND: Intracranial aneurysms (ICA) if inadequately treated may result in serious morbidity and mortality. Wide-neck; large/giant, fusiform, and dissecting aneurysms are not well treated using the conventional coil embolization technique. Recent advance in endovascular treatment and technology has introduced flow diverter devices including pipeline embolization devices (PED) and Silk stents that have been shown to be more effective in treating these more complicated aneurysms. Flow Diverter devices offer a more physiologic approach to ICA treatment.METHODS: We conducted a retrospective chart review of 23 adult patients who underwent aneurysm treatment utilizing the pipeline stent at Duke University Medical Center from July 2011 to March 2013.RESULTS: Majority of patients (19, 82.7%) showed angiographic evidence of complete obliteration of aneurysm at 6 months follow-up, with sustained clinical improvement on modified Rankin scale score. All of the patients tolerated the procedure well with no intra-operative hemorrhage or intra-operative thromboembolic complications.CONCLUSIONS: Our experience shows that use of PED offers a safe and effective strategy for treatment of complex ICA. Larger prospective studies are needed to confirm these observations.

U2 - 10.4103/1793-5482.131057

DO - 10.4103/1793-5482.131057

M3 - Article

C2 - 24891883

SN - 1793-5482

VL - 9

SP - 3

EP - 6

JO - Asian Journal of Neurosurgery

JF - Asian Journal of Neurosurgery

IS - 1

ER -

Use of pipeline flow diverting stents for wide neck intracranial aneurysms: A retrospective institutional review

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