TY - JOUR
T1 - Use of e-cigarettes, traditional combustible cigarettes, and high sensitivity C-reactive protein
T2 - The Cross Cohort Collaboration
AU - Yao, Zhiqi
AU - Tasdighi, Erfan
AU - Dardari, Zeina A.
AU - Erhabor, John
AU - Jha, Kunal K.
AU - Osuji, Ngozi
AU - Rajan, Tanuja
AU - Boakye, Ellen
AU - Rodriguez, Carlos J.
AU - Lima, Joao A.C.
AU - Judd, Suzanne E.
AU - Feldman, Theodore
AU - Fialkow, Jonathan A.
AU - Vasan, Ramachandran S.
AU - El Shahawy, Omar
AU - Benjamin, Emelia J.
AU - Bhatnagar, Aruni
AU - DeFilippis, Andrew P.
AU - Nasir, Khurram
AU - Blaha, Michael J.
N1 - Publisher Copyright:
© 2024 Elsevier Inc.
PY - 2025/2
Y1 - 2025/2
N2 - This cross-sectional study included 18,797 participants from 6 longitudinal cohorts (CARDIA, FHS Gen III, HCHS/SOL, MESA, MiHeart, and REGARDS), and 5,806 of them had high-sensitivity C-reactive protein (hs-CRP) measurements. We found that exclusive electronic cigarette (EC) use was associated with significantly lower hs-CRP levels compared to exclusive combustible cigarette use, suggesting a potentially lower inflammatory burden. hs-CRP levels in dual users and former smokers currently using EC were comparable to those observed in exclusive cigarette smokers. Exclusive EC users showed no significant difference in hs-CRP levels compared to never cigarette smokers. These findings have important implications for tobacco regulation, public health, and clinical practice, highlighting the need for continued monitoring of potential EC-related health impacts.
AB - This cross-sectional study included 18,797 participants from 6 longitudinal cohorts (CARDIA, FHS Gen III, HCHS/SOL, MESA, MiHeart, and REGARDS), and 5,806 of them had high-sensitivity C-reactive protein (hs-CRP) measurements. We found that exclusive electronic cigarette (EC) use was associated with significantly lower hs-CRP levels compared to exclusive combustible cigarette use, suggesting a potentially lower inflammatory burden. hs-CRP levels in dual users and former smokers currently using EC were comparable to those observed in exclusive cigarette smokers. Exclusive EC users showed no significant difference in hs-CRP levels compared to never cigarette smokers. These findings have important implications for tobacco regulation, public health, and clinical practice, highlighting the need for continued monitoring of potential EC-related health impacts.
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U2 - 10.1016/j.ahj.2024.10.012
DO - 10.1016/j.ahj.2024.10.012
M3 - Article
C2 - 39461654
AN - SCOPUS:85209588237
SN - 0002-8703
VL - 280
SP - 1
EP - 6
JO - American Heart Journal
JF - American Heart Journal
ER -