Uptake and toxicology of nanoparticles

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

In both nanotoxicology and nanomedicine, the cellular uptake of particles is a crucial first step determining ensuing biological responses. This is a multifaceted process dependent upon particle dynamics under the action of diffusion and sedimentation, the influence of biological media proteins which coat the particles and the complex interactions with cell membranes and their surface molecules. This chapter reviews the current state of knowledge in this area and provides an overview of future work towards the standardisation of measurements and analysis related to nanoparticle uptake in cells.

Original languageEnglish
Pages (from-to)123-138
Number of pages16
JournalFrontiers of Nanoscience
Volume5
DOIs
StatePublished - Sep 25 2013

Keywords

  • Bio-nanotechnology
  • Nanomedicine
  • Nanoparticle
  • Particle-cell interactions
  • Toxicity

ASJC Scopus subject areas

  • Materials Science(all)
  • Biomedical Engineering
  • Bioengineering

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