In both nanotoxicology and nanomedicine, the cellular uptake of particles is a crucial first step determining ensuing biological responses. This is a multifaceted process dependent upon particle dynamics under the action of diffusion and sedimentation, the influence of biological media proteins which coat the particles and the complex interactions with cell membranes and their surface molecules. This chapter reviews the current state of knowledge in this area and provides an overview of future work towards the standardisation of measurements and analysis related to nanoparticle uptake in cells.
|Number of pages||16|
|Journal||Frontiers of Nanoscience|
|State||Published - Sep 25 2013|
- Particle-cell interactions
ASJC Scopus subject areas
- Materials Science(all)
- Biomedical Engineering