Update: prostate cancer early detection clinical practice guidelines.

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Histopathologic analysis of a biopsy specimen of the prostate, examined to ascertain the presence of malignancy, can result in 4 possible diagnostic scenarios: (1) prostate cancer, (2) no evidence of cancer, (3) high-grade prostatic intraepithelial neoplasia, and (4) atypical small-gland proliferation suggestive of malignancy but not diagnostic. Until new studies provide a better method for selecting patients to undergo rebiopsy, patients diagnosed with high-grade prostatic intraepithelial neoplasia from a single core biopsy should undergo rebiopsy. A diagnosis of atypical glands suggestive of malignancy indicates that a rebiopsy should be performed because the chances of finding an invasive carcinoma are high.

Original languageEnglish (US)
JournalJournal of the National Comprehensive Cancer Network : JNCCN
Volume1 Suppl 1
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Oncology


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