Update in allergy and immunology

In this Update, 10 academic allergy and immunology specialists helped select, from 20 journals, papers published in 2005 that provided the greatest insight into the mechanisms and treatment of allergic and immune disorders. The papers are categorized into 3 themes: mechanisms of allergic disease, with insight into pathogenesis or treatment; therapy for allergic disease, including controversial or novel approaches for allergy treatment; and immune deficiency, with particular insight into the pathogenesis of common variable immunodeficiency (CVID).