Unraveling stress-induced toxicity properties of graphene oxide and the underlying mechanism

Wendi Zhang, Chi Wang, Zhongjun Li, Zhenzhen Lu, Yiye Li, Jun Jie Yin, Yu Ting Zhou, Xingfa Gao, Ying Fang, Guangjun Nie, Yuliang Zhao

Research output: Contribution to journalArticlepeer-review

193 Scopus citations

Abstract

Graphene oxide shows stress-induced toxicity properties in vivo under different pathophysiological conditions. A dual-path chemical mechanism, involving the overproduction of hydroxyl radicals and the formation of oxidizing cytochrome c intermediates, is responsible for the toxicity properties.

Original languageEnglish (US)
Pages (from-to)5391-5397
Number of pages7
JournalAdvanced Materials
Volume24
Issue number39
DOIs
StatePublished - Oct 9 2012

Keywords

  • electron transfer
  • functional materials
  • graphene oxide
  • nanotoxicity

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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