Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications

Assaf Zinger

doi:10.1016/j.jconrel.2023.04.040

Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications

Assaf Zinger

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

In this contribution to the Orations - New Horizons of the Journal of Controlled Release, I present design strategies for the two main biomimetic nanoparticles (BNP) groups: BNP composed of isolated cell membrane proteins, and BNP composed of the native cell membrane. I furthermore describe BNP fabrication methods and analyze their advantages and challenges. Finally, I suggest future therapeutic applications of each BNP group and propose a new revolutionary concept for their use.

Original language	English (US)
Pages (from-to)	591-600
Number of pages	10
Journal	Journal of Controlled Release
Volume	358
DOIs	https://doi.org/10.1016/j.jconrel.2023.04.040
State	Published - Jun 2023

Keywords

Biomimetic nanoparticles
Cell membrane
Drug delivery
Nanomedicine
Translational therapeutics
Nanoparticles
Membrane Proteins/metabolism
Biomimetics/methods
Cell Membrane/metabolism
Biomimetic Materials
Drug Delivery Systems/methods

ASJC Scopus subject areas

Pharmaceutical Science

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10.1016/j.jconrel.2023.04.040

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title = "Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications",

abstract = "In this contribution to the Orations - New Horizons of the Journal of Controlled Release, I present design strategies for the two main biomimetic nanoparticles (BNP) groups: BNP composed of isolated cell membrane proteins, and BNP composed of the native cell membrane. I furthermore describe BNP fabrication methods and analyze their advantages and challenges. Finally, I suggest future therapeutic applications of each BNP group and propose a new revolutionary concept for their use.",

keywords = "Biomimetic nanoparticles, Cell membrane, Drug delivery, Nanomedicine, Translational therapeutics, Nanoparticles, Membrane Proteins/metabolism, Biomimetics/methods, Cell Membrane/metabolism, Biomimetic Materials, Drug Delivery Systems/methods",

author = "Assaf Zinger",

note = "Publisher Copyright: {\textcopyright} 2023",

year = "2023",

month = jun,

doi = "10.1016/j.jconrel.2023.04.040",

language = "English (US)",

volume = "358",

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T1 - Unleashing the potential of cell biomimetic nanoparticles

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AU - Zinger, Assaf

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N2 - In this contribution to the Orations - New Horizons of the Journal of Controlled Release, I present design strategies for the two main biomimetic nanoparticles (BNP) groups: BNP composed of isolated cell membrane proteins, and BNP composed of the native cell membrane. I furthermore describe BNP fabrication methods and analyze their advantages and challenges. Finally, I suggest future therapeutic applications of each BNP group and propose a new revolutionary concept for their use.

AB - In this contribution to the Orations - New Horizons of the Journal of Controlled Release, I present design strategies for the two main biomimetic nanoparticles (BNP) groups: BNP composed of isolated cell membrane proteins, and BNP composed of the native cell membrane. I furthermore describe BNP fabrication methods and analyze their advantages and challenges. Finally, I suggest future therapeutic applications of each BNP group and propose a new revolutionary concept for their use.

KW - Biomimetic nanoparticles

KW - Cell membrane

KW - Drug delivery

KW - Nanomedicine

KW - Translational therapeutics

KW - Nanoparticles

KW - Membrane Proteins/metabolism

KW - Biomimetics/methods

KW - Cell Membrane/metabolism

KW - Biomimetic Materials

KW - Drug Delivery Systems/methods

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DO - 10.1016/j.jconrel.2023.04.040

M3 - Article

C2 - 37146767

AN - SCOPUS:85160012217

SN - 0168-3659

VL - 358

SP - 591

EP - 600

JO - Journal of Controlled Release

JF - Journal of Controlled Release

ER -

Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications

Abstract

Keywords

ASJC Scopus subject areas

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