Uncertainties remain in the catabolism of valine

Dwayne A. Wolf; Hugh A. Akers

doi:10.1016/0968-0004(86)90147-7

Uncertainties remain in the catabolism of valine

Dwayne A. Wolf, Hugh A. Akers

Houston Methodist

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The oxidative degradation of valine is known to proceed through a methylmalonate semialdehyde intermediate to succinyl-CoA. Good evidence suggests that at least one C₃ intermediate is involved in the conversion of methylmalonate semialdehyde to succinyl-CoA. However, the details of this conversion, at least in higher organisms, remain unclear.

Original language	English (US)
Pages (from-to)	390-392
Number of pages	3
Journal	Trends in Biochemical Sciences
Volume	11
Issue number	10
DOIs	https://doi.org/10.1016/0968-0004(86)90147-7
State	Published - Oct 1986

ASJC Scopus subject areas

Biochemistry
Molecular Biology

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10.1016/0968-0004(86)90147-7

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title = "Uncertainties remain in the catabolism of valine",

abstract = "The oxidative degradation of valine is known to proceed through a methylmalonate semialdehyde intermediate to succinyl-CoA. Good evidence suggests that at least one C3 intermediate is involved in the conversion of methylmalonate semialdehyde to succinyl-CoA. However, the details of this conversion, at least in higher organisms, remain unclear.",

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AU - Akers, Hugh A.

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N2 - The oxidative degradation of valine is known to proceed through a methylmalonate semialdehyde intermediate to succinyl-CoA. Good evidence suggests that at least one C3 intermediate is involved in the conversion of methylmalonate semialdehyde to succinyl-CoA. However, the details of this conversion, at least in higher organisms, remain unclear.

AB - The oxidative degradation of valine is known to proceed through a methylmalonate semialdehyde intermediate to succinyl-CoA. Good evidence suggests that at least one C3 intermediate is involved in the conversion of methylmalonate semialdehyde to succinyl-CoA. However, the details of this conversion, at least in higher organisms, remain unclear.

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JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

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Uncertainties remain in the catabolism of valine

Abstract

ASJC Scopus subject areas

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