Two triterpenoids and other constituents from Petasites tricholobus

Wei Dong Xie, Qi Zhang, Ping Lin Li, Zhong Jian Jia

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Two migrated ursane skeleton triterpenoids, one is D:B-friedoursane- 3α,16α-dihydroxy-7α,8α-epoxy-5(10)-ene, named petatrichol A (1) and the other one represents a novel triterpenoid carbon framework, named petatrichol B (2), along with 10 known compounds were isolated from the rhizome of Petasites tricholobus. Their structures were elucidated on the basis of spectroscopic methods (IR, EIMS, HRMS, 1D and 2D NMR). The triterpenoids were assayed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis. Compounds 1 and 2 exhibited significant antibacterial activity against B. subtilis.

Original languageEnglish (US)
Pages (from-to)2340-2345
Number of pages6
JournalPhytochemistry
Volume66
Issue number19
DOIs
StatePublished - Oct 2005

Keywords

  • Antibacterial activity
  • Compositae
  • Petasites tricholobus
  • Triterpenoid

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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