Tumor-targeting with novel non-benzoyl 6-substituted straight chain pyrrolo[2,3-d ]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesis

Yiqiang Wang, Christina Cherian, Steven Orr, Shermaine Mitchell-Ryan, Zhanjun Hou, Sudhir Raghavan, Larry H. Matherly, Aleem Gangjee

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