Tumor Lysis Syndrome. A Unique Solute Disturbance

Penelope Z. Strauss, Shannan K. Hamlin, Johnny Dang

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Tumor lysis syndrome (TLS) is a life-threatening disorder that is an oncologic emergency. Risk factors for TLS are well known, but the current literature shows case descriptions of unexpected acute TLS. Solid tumors and untreated hematologic tumors can lyse under various circumstances in children and adults. International guidelines and recommendations, including the early involvement of the critical care team, have been put forward to help clinicians properly manage the syndrome. Advanced practice nurses may be in the position of triaging and initiating treatment of patients with TLS, and need a thorough understanding of the syndrome and its treatment.

Original languageEnglish (US)
JournalNursing Clinics of North America
StateAccepted/In press - 2017


  • Hyperkalemia
  • Hyperphosphatemia
  • Hyperuricemia
  • Malignant cell metabolism
  • Tumor lysis syndrome

ASJC Scopus subject areas

  • Nursing(all)


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