Tumor-like lesions of bone

MANY BONE LESIONS simulate neoplasms, including eosinophilic granuloma, fibrous dysplasia, brown tumor of hyperparathyroidism, Paget's disease, and osteomyelitis, and are well-known clinicopathologic entities. Although most of these merit little attention, other lesions cause significant diagnostic problems for the examining pathologist. Recognizing these latter entities avoids an erroneous diagnosis and unnecessary treatment. In this article, we focus on intraosseous ganglion, subchondral cyst, solitary bone cyst, aneurysmal bone cyst, chest wall hamartoma, fibroosseous proliferations, and stress fractures, because of the difficulties they present clinically and pathologically.