TY - JOUR
T1 - Trigeminocardiac reflex
T2 - The current clinical and physiological knowledge
AU - Chowdhury, Tumul
AU - Mendelowith, David
AU - Golanov, Eugene
AU - Spiriev, Toma
AU - Arasho, Belachew
AU - Sandu, Nora
AU - Sadr-Eshkevari, Pooyan
AU - Meuwly, Cyrill
AU - Schaller, Bernhard
N1 - Publisher Copyright:
© 2014 Wolters Kluwer Health, Inc.
PY - 2015/3/27
Y1 - 2015/3/27
N2 - The trigeminocardiac reflex (TCR) is defined as the sudden onset of parasympathetic dysrhythmia, sympathetic hypotension, apnea, or gastric hypermotility during stimulation of any of the sensory branches of the trigeminal nerve. Clinically, the TCR has been reported in all the surgical procedures in which a structure innervated by the trigeminal nerve is involved. Although, there is an abundant literature with reports of incidences and risk factors of the TCR; the physiological significance and function of this brainstem reflex has not yet been fully elucidated. In addition, there are complexities within the TCR that requires examination and clarification. There is also a growing need to discuss its cellular mechanism and functional consequences. Therefore, the current review provides an updated examination of the TCR with a particular focus on the mechanisms and diverse nature of the TCR.
AB - The trigeminocardiac reflex (TCR) is defined as the sudden onset of parasympathetic dysrhythmia, sympathetic hypotension, apnea, or gastric hypermotility during stimulation of any of the sensory branches of the trigeminal nerve. Clinically, the TCR has been reported in all the surgical procedures in which a structure innervated by the trigeminal nerve is involved. Although, there is an abundant literature with reports of incidences and risk factors of the TCR; the physiological significance and function of this brainstem reflex has not yet been fully elucidated. In addition, there are complexities within the TCR that requires examination and clarification. There is also a growing need to discuss its cellular mechanism and functional consequences. Therefore, the current review provides an updated examination of the TCR with a particular focus on the mechanisms and diverse nature of the TCR.
KW - autonomous nerve system
KW - brainstem reflex
KW - central
KW - chronic
KW - peripheral
KW - skull-base surgery
KW - trigeminocardiac reflex
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U2 - 10.1097/ANA.0000000000000065
DO - 10.1097/ANA.0000000000000065
M3 - Review article
C2 - 25602626
AN - SCOPUS:84925873451
SN - 0898-4921
VL - 27
SP - 136
EP - 147
JO - Journal of Neurosurgical Anesthesiology
JF - Journal of Neurosurgical Anesthesiology
IS - 2
ER -