@article{8c8e4b5068ea4a80b2cf463f6f9129d1,
title = "Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems",
abstract = "Pragmatic clinical trials are increasingly common because they have the potential to yield findings that are directly translatable to real-world healthcare settings. Pragmatic clinical trials need to integrate research into clinical workflow without placing an undue burden on the delivery system. This requires a research partnership between investigators and healthcare system representatives. This paper, organized as a series of case studies drawn from our experience in the NIH Health Care Systems Research Collaboratory, presents guidance from informational interviews of physician–scientists, health services researchers, and delivery system leaders who recently launched pragmatic clinical trials.",
keywords = "Pragmatic trials",
author = "Larson, {Eric B.} and Chris Tachibana and Ella Thompson and Coronado, {Gloria D.} and Lynn DeBar and Dember, {Laura M.} and Stacey Honda and Huang, {Susan S.} and Jarvik, {Jeffrey G.} and Christine Nelson and Edward Septimus and Greg Simon and Johnson, {Karin E.}",
note = "Funding Information: This work is supported by the National Institutes of Health (NIH) Common Fund, through cooperative agreement U54 AT007748 from the Office of Strategic Coordination within the Office of the NIH Director, as well as NIH Awards 5UH3DK102384-03, 5UH3CA188640-03, 5UH3NS088731-03, 5UH3AR066795-03, 4UH3MH007755-02 and 5UH3AI113337-03. The views presented here are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health. The sponsor did not have a role in designing, researching and writing this paper or deciding to submit it for publication. Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",
year = "2016",
doi = "10.1016/j.hjdsi.2015.07.005",
language = "English (US)",
volume = "4",
pages = "138--141",
journal = "Healthcare",
issn = "2213-0764",
publisher = "Elsevier BV",
number = "3",
}