Treatment results of radiotherapy for squamous cell carcinoma of the cheek mucosa

K. Kubo, S. Furukawa, H. Fuchihata, M. Fujita, K. Shimizutani, H. Ikeda, T. Inoue

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2 Scopus citations


The results of radiotherapeutic treatment in 71 patients with squamous cell carcinoma of the cheek mucosa were reviewed. The actuarial 5-year local control rate was 100% for T1 (8 patients), 62% for T2 (43), 65% for T3 (17) and 0% for T4 (3). The patients were divided into four groups according to treatment modality; group 1 was treated by radiotherapy alone (R), group 2 by radiotherapy combined with chemotherapy of BLM or PEP (R + C), group 3 by external radiotherapy followed by surgery (R + S) and group 4 by a combination of radiotherapy, chemotherapy and surgery (R + C + S). The 5-year local control rate was 44% for R (11 patients), 61% for R + C (39), 63% for R + S (6) and 80% for R + C + S (15). Nine of 14 cases or 64% of the surgical specimens in the R + C + S group showed no tumor cells microscopically, a rate comparable with the 5-year local control rate of the R + C group. Including the results of secondary treatment by surgery for recurrent cases, the ultimate local control rate was 83% in both the R and R + C groups. The local control rate was 88% for carcinoma located in the anterior half of the cheek and 53% for that in the posterior cheek. The results suggested that tumors extending to the bucco-alveolar sulci would be more difficult to control by radiotherapy alone, with or without chemotherapy.

Original languageEnglish (US)
Pages (from-to)199-207
Number of pages9
JournalNippon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica
Issue number2
StatePublished - Feb 25 1992

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Oncology


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