TY - JOUR
T1 - Treatment options for atypical optic neuritis
AU - Malik, Amina
AU - Ahmed, Maryam
AU - Golnik, Karl
N1 - Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Context: Optic neuritis (ON) is defined as inflammation of the optic nerve and can have various etiologies. The most common presentation in the US is demyelinating, or «typical» ON, usually associated with multiple sclerosis. This is in contrast to «atypical» causes of ON, which differ in their clinical presentation, management, and prognosis. These atypical cases are characterized by lack of eye pain, exudates, and hemorrhages on exam, very severe, bilateral or progressive visual loss, or with failure to recover vision. Aims: The aim was to describe the clinical presentations of atypical ON and their treatments. Settings and Design: Review article. Materials and Methods: Literature review. Results: Types of atypical ON identified include neuromyelitis optica, autoimmune optic neuropathy, chronic relapsing inflammatory optic neuropathy, idiopathic recurrent neuroretinitis, and optic neuropathy associated with systemic diseases. Atypical ON usually requires corticosteroid treatment and often will require aggressive immunosuppression. Conclusions: Unlike demyelinating ON, atypical ON requires treatment to preserve vision.
AB - Context: Optic neuritis (ON) is defined as inflammation of the optic nerve and can have various etiologies. The most common presentation in the US is demyelinating, or «typical» ON, usually associated with multiple sclerosis. This is in contrast to «atypical» causes of ON, which differ in their clinical presentation, management, and prognosis. These atypical cases are characterized by lack of eye pain, exudates, and hemorrhages on exam, very severe, bilateral or progressive visual loss, or with failure to recover vision. Aims: The aim was to describe the clinical presentations of atypical ON and their treatments. Settings and Design: Review article. Materials and Methods: Literature review. Results: Types of atypical ON identified include neuromyelitis optica, autoimmune optic neuropathy, chronic relapsing inflammatory optic neuropathy, idiopathic recurrent neuroretinitis, and optic neuropathy associated with systemic diseases. Atypical ON usually requires corticosteroid treatment and often will require aggressive immunosuppression. Conclusions: Unlike demyelinating ON, atypical ON requires treatment to preserve vision.
KW - Atypical optic neuritis
KW - autoimmunity
KW - multiple sclerosis
KW - neuromyelitis optica
KW - neuroretinitis
KW - optic neuritis
KW - optic neuropathy
UR - http://www.scopus.com/inward/record.url?scp=84916628076&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84916628076&partnerID=8YFLogxK
U2 - 10.4103/0301-4738.145986
DO - 10.4103/0301-4738.145986
M3 - Review article
C2 - 25449930
AN - SCOPUS:84916628076
VL - 62
SP - 982
EP - 984
JO - Indian Journal of Ophthalmology
JF - Indian Journal of Ophthalmology
SN - 0301-4738
IS - 10
ER -