Treatment of recurrent cerebrovascular disease: Review of a 10-year experience

K. A. Coyle, R. B. Smith, B. C. Gray, A. A. Salam, T. F. Dodson, E. L. Chaikof, A. B. Lumsden, G. M. Lawrie, T. R S Harvard, W. H. Edwards, B. Keagy, B. Smith, O. H. Frazier

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Objective: The authors determined whether carotid endarterectomy in patients with recurrent cerebrovascular disease poses a greater perioperative risk than for those individuals undergoing first-time carotid endarterectomy. Summary Background Data: A percentage of patients undergoing carotid endarterectomy for atherosclerosis experience recurrent cerebrovascular disease. Reoperation may be difficult because of postoperative scarring of the soft tissues of the neck and the carotid artery itself. Such patients were believed to be at greater risk for perioperative morbidity than those undergoing first-time carotid endarterectomy. Methods: To address this concern, the authors retrospectively reviewed their experience with 69 patients who underwent repeat carotid endarterectomies over a recent 10-year period of time. This subgroup represented 6.4% of 1072 total carotid endarterectomies performed during the same time period. The average extent of stenosis on the operated side was 81% and the time elapsed after previous endarterectomy averaged 83 months. Twelve patients (17.4%) had contralateral internal carotid occlusion, and 30 patients (43.5%) had undergone previous endarterectomies on the contralateral side. Results: Complications within 30 days of operation included two deaths (2.9%) and one stroke (1.4%), for a combined stroke and death rate of 4.3%. Six patients developed cervical hematomas requiring drainage; one of these had rupture of a saphenous vein patch. No patient had a significant cranial nerve injury in the reoperative group, whereas 2.0% of patients undergoing first-time carotid endarterectomy had cranial nerve injuries. Overall, these results compared favorably with a combined stroke and death rate of 4.0% among 1003 patients who underwent first-time carotid endarterectomy during the same period. Conclusions: This review suggests that repeat carotid endarterectomy can be performed safely in individuals with severe recurrent carotid stenosis, with morbidity and mortality rates similar to those for patients undergoing first time carotid endarterectomies. For this population, reoperative carotid endarterectomy represents a safe and important mechanism for the prevention at stroke.

Original languageEnglish (US)
Pages (from-to)517-524
Number of pages8
JournalAnnals of surgery
Issue number5
StatePublished - May 1995

ASJC Scopus subject areas

  • Surgery


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