Treatment of ocular surface squamous neoplasia with topical Aloe vera drops

Mausam R. Damani, Ankoor R. Shah, Carol L. Karp, Stephen E. Orlin

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Purpose: To report a case of ocular surface squamous neoplasia (OSSN) that resolved with topical Aloe vera eye drop treatment.

Methods: A 64-year-old Hispanic woman with a lesion typical for OSSN in her left eye was followed up with multiple clinical examinations and ocular surface photographs to document changes over time with A. vera-based topical treatment.

Results: The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. At follow-up visits, the lesion was noted to regress until it finally resolved 3 months after commencing treatment. No additional topical medications were used, and she has remained tumor free for 6 years.

Conclusions: Ongoing research is warranted because A. vera may represent a new therapeutic class of medications for OSSN treatment.

Original languageEnglish (US)
Pages (from-to)87-89
Number of pages3
Issue number1
StatePublished - Jan 12 2015


  • Aloe vera
  • Chemotherapy
  • Ocular surface squamous neoplasia

ASJC Scopus subject areas

  • Ophthalmology


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