Treatment of ocular surface squamous neoplasia with topical Aloe vera drops

Mausam R. Damani; Ankoor R. Shah; Carol L. Karp; Stephen E. Orlin

doi:10.1097/ICO.0000000000000296

Treatment of ocular surface squamous neoplasia with topical Aloe vera drops

Mausam R. Damani, Ankoor R. Shah, Carol L. Karp, Stephen E. Orlin

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Purpose: To report a case of ocular surface squamous neoplasia (OSSN) that resolved with topical Aloe vera eye drop treatment.

Methods: A 64-year-old Hispanic woman with a lesion typical for OSSN in her left eye was followed up with multiple clinical examinations and ocular surface photographs to document changes over time with A. vera-based topical treatment.

Results: The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. At follow-up visits, the lesion was noted to regress until it finally resolved 3 months after commencing treatment. No additional topical medications were used, and she has remained tumor free for 6 years.

Conclusions: Ongoing research is warranted because A. vera may represent a new therapeutic class of medications for OSSN treatment.

Original language	English (US)
Pages (from-to)	87-89
Number of pages	3
Journal	Cornea
Volume	34
Issue number	1
DOIs	https://doi.org/10.1097/ICO.0000000000000296
State	Published - Jan 12 2015

Keywords

Aloe vera
Chemotherapy
Ocular surface squamous neoplasia

ASJC Scopus subject areas

Ophthalmology

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10.1097/ICO.0000000000000296

Cite this

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title = "Treatment of ocular surface squamous neoplasia with topical Aloe vera drops",

abstract = "Purpose: To report a case of ocular surface squamous neoplasia (OSSN) that resolved with topical Aloe vera eye drop treatment.Methods: A 64-year-old Hispanic woman with a lesion typical for OSSN in her left eye was followed up with multiple clinical examinations and ocular surface photographs to document changes over time with A. vera-based topical treatment.Results: The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. At follow-up visits, the lesion was noted to regress until it finally resolved 3 months after commencing treatment. No additional topical medications were used, and she has remained tumor free for 6 years.Conclusions: Ongoing research is warranted because A. vera may represent a new therapeutic class of medications for OSSN treatment.",

keywords = "Aloe vera, Chemotherapy, Ocular surface squamous neoplasia",

author = "Damani, {Mausam R.} and Shah, {Ankoor R.} and Karp, {Carol L.} and Orlin, {Stephen E.}",

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T1 - Treatment of ocular surface squamous neoplasia with topical Aloe vera drops

AU - Damani, Mausam R.

AU - Shah, Ankoor R.

AU - Karp, Carol L.

AU - Orlin, Stephen E.

PY - 2015/1/12

Y1 - 2015/1/12

N2 - Purpose: To report a case of ocular surface squamous neoplasia (OSSN) that resolved with topical Aloe vera eye drop treatment.Methods: A 64-year-old Hispanic woman with a lesion typical for OSSN in her left eye was followed up with multiple clinical examinations and ocular surface photographs to document changes over time with A. vera-based topical treatment.Results: The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. At follow-up visits, the lesion was noted to regress until it finally resolved 3 months after commencing treatment. No additional topical medications were used, and she has remained tumor free for 6 years.Conclusions: Ongoing research is warranted because A. vera may represent a new therapeutic class of medications for OSSN treatment.

AB - Purpose: To report a case of ocular surface squamous neoplasia (OSSN) that resolved with topical Aloe vera eye drop treatment.Methods: A 64-year-old Hispanic woman with a lesion typical for OSSN in her left eye was followed up with multiple clinical examinations and ocular surface photographs to document changes over time with A. vera-based topical treatment.Results: The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. At follow-up visits, the lesion was noted to regress until it finally resolved 3 months after commencing treatment. No additional topical medications were used, and she has remained tumor free for 6 years.Conclusions: Ongoing research is warranted because A. vera may represent a new therapeutic class of medications for OSSN treatment.

KW - Aloe vera

KW - Chemotherapy

KW - Ocular surface squamous neoplasia

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Treatment of ocular surface squamous neoplasia with topical Aloe vera drops

Abstract

Keywords

ASJC Scopus subject areas

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