Treatment controversies in medulloblastoma

Murali Chintagumpala, Stacey Berg, Susan M. Blaney

Research output: Contribution to journalReview article

19 Scopus citations

Abstract

Medulloblastoma, the most common primary malignant brain tumor in children, is a radiosensitive and chemosensitive tumor. Nevertheless, medulloblastoma remains a management challenge for the clinical oncologist, because the optimal sequence and dosage for each treatment modality has not yet been defined. In addition, effective management strategies for medulloblastoma may result in profound neuroendocrine and neuropsychologic sequelae. In this article, we review the clinical and biologic prognostic factors for classifying medulloblastoma, current strategies for the management of this disease, and potential strategies to prevent or minimize long-term treatment sequelae.

Original languageEnglish (US)
Pages (from-to)154-159
Number of pages6
JournalCurrent Opinion in Oncology
Volume13
Issue number3
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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