The relationship between age and neurocognitive functioning following proton beam radiotherapy (PRT) in low- and intermediate-grade gliomas (LIGG) has yet to be examined. Eighteen LIGG patients treated with PRT were prospectively enrolled and received annual neurocognitive evaluations of perceptual/verbal reasoning, working memory, and processing speed postradiotherapy. The median age at diagnosis was 8.2 years (range 1.0–14.7) and the median age at PRT was 9.9 years (range 4.2–17.0). Patients' neurocognitive performance did not change on any measure following PRT (p ≥.142). We did not observe significant changes in cognitive function over time among a small group of LIGG patients treated with PRT.
- low-grade glioma
- pediatric brain tumor
- proton radiotherapy
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health