Treating hypertension in patients with left ventricular dysfunction: Hitting the fairway and avoiding the rough

Research output: Contribution to journalArticle

Samuel W. Joffe, Robert A. Phillips

Hypertension is a major risk factor in the development of heart failure (HF), yet current guidelines do not specify a target blood pressure (BP) for patients with established systolic or diastolic left ventricular (LV) dysfunction. While no randomized controlled trial (RCT) has been conducted to specify the optimal blood pressure in these patients, numerous trials have demonstrated the benefits of certain classes of medications and treatment strategies in patients with HF. Important factors to consider in treating hypertension in patients with HF include the type of HF (reduced vs. preserved ejection fraction), the etiology (ischemic vs. nonischemic), the severity of symptoms if any, the baseline blood pressure, as well as a wide variety of patient-specific factors. This paper reviews current evidence to address the question, "What should be the blood pressure goal in patients with asymptomatic and symptomatic left ventricular dysfunction?" We suggest a target blood pressure of 120-140/70-90 mm Hg in most cases, with lower pressures generally preferable if tolerated.

Original languageEnglish (US)
Pages (from-to)157-164
Number of pages8
JournalCurrent heart failure reports
Volume10
Issue number2
DOIs
StatePublished - Jun 1 2013

PMID: 23563890

Altmetrics

Cite this

Standard

Treating hypertension in patients with left ventricular dysfunction : Hitting the fairway and avoiding the rough. / Joffe, Samuel W.; Phillips, Robert A.

In: Current heart failure reports, Vol. 10, No. 2, 01.06.2013, p. 157-164.

Research output: Contribution to journalArticle

Harvard

Joffe, SW & Phillips, RA 2013, 'Treating hypertension in patients with left ventricular dysfunction: Hitting the fairway and avoiding the rough' Current heart failure reports, vol. 10, no. 2, pp. 157-164. https://doi.org/10.1007/s11897-013-0137-9

APA

Joffe, S. W., & Phillips, R. A. (2013). Treating hypertension in patients with left ventricular dysfunction: Hitting the fairway and avoiding the rough. Current heart failure reports, 10(2), 157-164. https://doi.org/10.1007/s11897-013-0137-9

Vancouver

Joffe SW, Phillips RA. Treating hypertension in patients with left ventricular dysfunction: Hitting the fairway and avoiding the rough. Current heart failure reports. 2013 Jun 1;10(2):157-164. https://doi.org/10.1007/s11897-013-0137-9

Author

Joffe, Samuel W. ; Phillips, Robert A. / Treating hypertension in patients with left ventricular dysfunction : Hitting the fairway and avoiding the rough. In: Current heart failure reports. 2013 ; Vol. 10, No. 2. pp. 157-164.

BibTeX

@article{3396883d2550420d960ec78135c1f97f,
title = "Treating hypertension in patients with left ventricular dysfunction: Hitting the fairway and avoiding the rough",
abstract = "Hypertension is a major risk factor in the development of heart failure (HF), yet current guidelines do not specify a target blood pressure (BP) for patients with established systolic or diastolic left ventricular (LV) dysfunction. While no randomized controlled trial (RCT) has been conducted to specify the optimal blood pressure in these patients, numerous trials have demonstrated the benefits of certain classes of medications and treatment strategies in patients with HF. Important factors to consider in treating hypertension in patients with HF include the type of HF (reduced vs. preserved ejection fraction), the etiology (ischemic vs. nonischemic), the severity of symptoms if any, the baseline blood pressure, as well as a wide variety of patient-specific factors. This paper reviews current evidence to address the question, {"}What should be the blood pressure goal in patients with asymptomatic and symptomatic left ventricular dysfunction?{"} We suggest a target blood pressure of 120-140/70-90 mm Hg in most cases, with lower pressures generally preferable if tolerated.",
keywords = "Aldosterone antagonist, Angiotensin converting enzyme inhibitor, Angiotensin receptor blocker, Beta blocker, Diastolic function, Diuretic, Heart failure, Hypertension, Systolic function, Ventricular dysfunction",
author = "Joffe, {Samuel W.} and Phillips, {Robert A.}",
year = "2013",
month = "6",
day = "1",
doi = "10.1007/s11897-013-0137-9",
language = "English (US)",
volume = "10",
pages = "157--164",
journal = "Current Heart Failure Reports",
issn = "1546-9530",
publisher = "Current Science, Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Treating hypertension in patients with left ventricular dysfunction

T2 - Current Heart Failure Reports

AU - Joffe, Samuel W.

AU - Phillips, Robert A.

PY - 2013/6/1

Y1 - 2013/6/1

N2 - Hypertension is a major risk factor in the development of heart failure (HF), yet current guidelines do not specify a target blood pressure (BP) for patients with established systolic or diastolic left ventricular (LV) dysfunction. While no randomized controlled trial (RCT) has been conducted to specify the optimal blood pressure in these patients, numerous trials have demonstrated the benefits of certain classes of medications and treatment strategies in patients with HF. Important factors to consider in treating hypertension in patients with HF include the type of HF (reduced vs. preserved ejection fraction), the etiology (ischemic vs. nonischemic), the severity of symptoms if any, the baseline blood pressure, as well as a wide variety of patient-specific factors. This paper reviews current evidence to address the question, "What should be the blood pressure goal in patients with asymptomatic and symptomatic left ventricular dysfunction?" We suggest a target blood pressure of 120-140/70-90 mm Hg in most cases, with lower pressures generally preferable if tolerated.

AB - Hypertension is a major risk factor in the development of heart failure (HF), yet current guidelines do not specify a target blood pressure (BP) for patients with established systolic or diastolic left ventricular (LV) dysfunction. While no randomized controlled trial (RCT) has been conducted to specify the optimal blood pressure in these patients, numerous trials have demonstrated the benefits of certain classes of medications and treatment strategies in patients with HF. Important factors to consider in treating hypertension in patients with HF include the type of HF (reduced vs. preserved ejection fraction), the etiology (ischemic vs. nonischemic), the severity of symptoms if any, the baseline blood pressure, as well as a wide variety of patient-specific factors. This paper reviews current evidence to address the question, "What should be the blood pressure goal in patients with asymptomatic and symptomatic left ventricular dysfunction?" We suggest a target blood pressure of 120-140/70-90 mm Hg in most cases, with lower pressures generally preferable if tolerated.

KW - Aldosterone antagonist

KW - Angiotensin converting enzyme inhibitor

KW - Angiotensin receptor blocker

KW - Beta blocker

KW - Diastolic function

KW - Diuretic

KW - Heart failure

KW - Hypertension

KW - Systolic function

KW - Ventricular dysfunction

UR - http://www.scopus.com/inward/record.url?scp=84883055306&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84883055306&partnerID=8YFLogxK

U2 - 10.1007/s11897-013-0137-9

DO - 10.1007/s11897-013-0137-9

M3 - Article

VL - 10

SP - 157

EP - 164

JO - Current Heart Failure Reports

JF - Current Heart Failure Reports

SN - 1546-9530

IS - 2

ER -

ID: 16808653