Transplantation for acute liver failure: Perioperative management

Randolph H. Steadman; Adriaan Van Rensburg; David J. Kramer

doi:10.1097/MOT.0b013e32833982dd

Transplantation for acute liver failure: Perioperative management

Randolph H. Steadman, Adriaan Van Rensburg, David J. Kramer

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Abstract

PURPOSE OF REVIEW: A number of conditions can lead to acute liver failure. Determining the cause has important prognostic implications that guide decisions regarding the likelihood of spontaneous recovery, or conversely, the need for transplantation. RECENT FINDINGS: Neurological deterioration is associated with intracranial hypertension, which requires meticulous management. The decision to employ invasive intracranial pressure monitoring is controversial because of associated risks and the lack of controlled studies. Recent literature addressing the use of intracranial pressure monitoring is reviewed. SUMMARY: Even tertiary care units that specialize in liver disease treat acute liver failure patients infrequently. Knowledge of the latest guidelines and treatment protocols can lead to improved patient care

Original language	English (US)
Pages (from-to)	368-373
Number of pages	6
Journal	Current opinion in organ transplantation
Volume	15
Issue number	3
DOIs	https://doi.org/10.1097/MOT.0b013e32833982dd
State	Published - Jun 2010

Keywords

Acute liver failure
Cerebral edema
Fulminant hepatic failure
Intracranial hypertension
Liver transplantation

ASJC Scopus subject areas

Immunology and Allergy
Transplantation

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10.1097/MOT.0b013e32833982dd

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title = "Transplantation for acute liver failure: Perioperative management",

abstract = "PURPOSE OF REVIEW: A number of conditions can lead to acute liver failure. Determining the cause has important prognostic implications that guide decisions regarding the likelihood of spontaneous recovery, or conversely, the need for transplantation. RECENT FINDINGS: Neurological deterioration is associated with intracranial hypertension, which requires meticulous management. The decision to employ invasive intracranial pressure monitoring is controversial because of associated risks and the lack of controlled studies. Recent literature addressing the use of intracranial pressure monitoring is reviewed. SUMMARY: Even tertiary care units that specialize in liver disease treat acute liver failure patients infrequently. Knowledge of the latest guidelines and treatment protocols can lead to improved patient care",

keywords = "Acute liver failure, Cerebral edema, Fulminant hepatic failure, Intracranial hypertension, Liver transplantation",

author = "Steadman, {Randolph H.} and {Van Rensburg}, Adriaan and Kramer, {David J.}",

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T1 - Transplantation for acute liver failure

T2 - Perioperative management

AU - Steadman, Randolph H.

AU - Van Rensburg, Adriaan

AU - Kramer, David J.

PY - 2010/6

Y1 - 2010/6

N2 - PURPOSE OF REVIEW: A number of conditions can lead to acute liver failure. Determining the cause has important prognostic implications that guide decisions regarding the likelihood of spontaneous recovery, or conversely, the need for transplantation. RECENT FINDINGS: Neurological deterioration is associated with intracranial hypertension, which requires meticulous management. The decision to employ invasive intracranial pressure monitoring is controversial because of associated risks and the lack of controlled studies. Recent literature addressing the use of intracranial pressure monitoring is reviewed. SUMMARY: Even tertiary care units that specialize in liver disease treat acute liver failure patients infrequently. Knowledge of the latest guidelines and treatment protocols can lead to improved patient care

AB - PURPOSE OF REVIEW: A number of conditions can lead to acute liver failure. Determining the cause has important prognostic implications that guide decisions regarding the likelihood of spontaneous recovery, or conversely, the need for transplantation. RECENT FINDINGS: Neurological deterioration is associated with intracranial hypertension, which requires meticulous management. The decision to employ invasive intracranial pressure monitoring is controversial because of associated risks and the lack of controlled studies. Recent literature addressing the use of intracranial pressure monitoring is reviewed. SUMMARY: Even tertiary care units that specialize in liver disease treat acute liver failure patients infrequently. Knowledge of the latest guidelines and treatment protocols can lead to improved patient care

KW - Acute liver failure

KW - Cerebral edema

KW - Fulminant hepatic failure

KW - Intracranial hypertension

KW - Liver transplantation

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Transplantation for acute liver failure: Perioperative management

Abstract

Keywords

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