Transmission of second-hand smoke sensitivity and smoking attitude in a family

Research output: Contribution to journalArticle

David Laszlo Tarnoki, Adam Domonkos Tarnoki, Levente Littvay, Zsofia Lazar, Kinga Karlinger, Andrea Agnes Molnar, Dora Melicher, Zsolt Garami, Viktor Berczi, Ildiko Horvath

Introduction and objective. The role of genetic factors in nicotine dependence is well understood, but no information is available on the inheritability of second-hand smoke (SHS) exposure sensitivity and their co-variance.

Materials and methods. 186 adult same-gender pairs of twin (146 monozygotic, 40 dizygotic; 44±17 years±SD) completed a questionnaire.

Results. The model showed a significant role of unshared environmental factors influencing the co-variance between smoking habit and SHS sensitivity (re=-0.191, 95% CI, -0.316 to -0.056, or the total phenotypic correlation of rph=-0.406, p<0.001) without evidence for genetic covariation. Age, gender and country-adjusted analysis indicated 51.5% heritability for smoking habit (95% confidence interval/CI/, 6.2 to 89.8%), 49.7% for SHS sensitivity (95%CI, 19.1–72.0%), 35.5% for general opinions on SHS exposure in restaurants/cafés (95%CI, 10.7–58.6%), and 16.9% in pubs/bars (95%CI, 0.0–49.0%).

Conclusions. The co-variance between SHS sensitivity and smoking habits is driven mainly by the unshared environment. SHS sensitivity is moderately inheritable. The considerable influence of environmental factors on general opinions on SHS exposure in designated indoor public venues emphasizes the importance of smoking bans and health behaviour interventions at the individual level in developing an anti-smoking attitude.

Original languageEnglish (US)
Pages (from-to)771-775
Number of pages5
JournalAnnals of Agricultural and Environmental Medicine
Volume21
Issue number4
DOIs
StatePublished - Jan 1 2014

PMID: 25528918

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Transmission of second-hand smoke sensitivity and smoking attitude in a family. / Tarnoki, David Laszlo; Tarnoki, Adam Domonkos; Littvay, Levente; Lazar, Zsofia; Karlinger, Kinga; Molnar, Andrea Agnes; Melicher, Dora; Garami, Zsolt; Berczi, Viktor; Horvath, Ildiko.

In: Annals of Agricultural and Environmental Medicine, Vol. 21, No. 4, 01.01.2014, p. 771-775.

Research output: Contribution to journalArticle

Harvard

Tarnoki, DL, Tarnoki, AD, Littvay, L, Lazar, Z, Karlinger, K, Molnar, AA, Melicher, D, Garami, Z, Berczi, V & Horvath, I 2014, 'Transmission of second-hand smoke sensitivity and smoking attitude in a family' Annals of Agricultural and Environmental Medicine, vol. 21, no. 4, pp. 771-775. https://doi.org/10.5604/12321966.1129931

APA

Tarnoki, D. L., Tarnoki, A. D., Littvay, L., Lazar, Z., Karlinger, K., Molnar, A. A., ... Horvath, I. (2014). Transmission of second-hand smoke sensitivity and smoking attitude in a family. Annals of Agricultural and Environmental Medicine, 21(4), 771-775. https://doi.org/10.5604/12321966.1129931

Vancouver

Tarnoki DL, Tarnoki AD, Littvay L, Lazar Z, Karlinger K, Molnar AA et al. Transmission of second-hand smoke sensitivity and smoking attitude in a family. Annals of Agricultural and Environmental Medicine. 2014 Jan 1;21(4):771-775. https://doi.org/10.5604/12321966.1129931

Author

Tarnoki, David Laszlo ; Tarnoki, Adam Domonkos ; Littvay, Levente ; Lazar, Zsofia ; Karlinger, Kinga ; Molnar, Andrea Agnes ; Melicher, Dora ; Garami, Zsolt ; Berczi, Viktor ; Horvath, Ildiko. / Transmission of second-hand smoke sensitivity and smoking attitude in a family. In: Annals of Agricultural and Environmental Medicine. 2014 ; Vol. 21, No. 4. pp. 771-775.

BibTeX

@article{e04b32de4b0246b6a916ef93534f952e,
title = "Transmission of second-hand smoke sensitivity and smoking attitude in a family",
abstract = "Introduction and objective. The role of genetic factors in nicotine dependence is well understood, but no information is available on the inheritability of second-hand smoke (SHS) exposure sensitivity and their co-variance.Materials and methods. 186 adult same-gender pairs of twin (146 monozygotic, 40 dizygotic; 44±17 years±SD) completed a questionnaire.Results. The model showed a significant role of unshared environmental factors influencing the co-variance between smoking habit and SHS sensitivity (re=-0.191, 95{\%} CI, -0.316 to -0.056, or the total phenotypic correlation of rph=-0.406, p<0.001) without evidence for genetic covariation. Age, gender and country-adjusted analysis indicated 51.5{\%} heritability for smoking habit (95{\%} confidence interval/CI/, 6.2 to 89.8{\%}), 49.7{\%} for SHS sensitivity (95{\%}CI, 19.1–72.0{\%}), 35.5{\%} for general opinions on SHS exposure in restaurants/caf{\'e}s (95{\%}CI, 10.7–58.6{\%}), and 16.9{\%} in pubs/bars (95{\%}CI, 0.0–49.0{\%}).Conclusions. The co-variance between SHS sensitivity and smoking habits is driven mainly by the unshared environment. SHS sensitivity is moderately inheritable. The considerable influence of environmental factors on general opinions on SHS exposure in designated indoor public venues emphasizes the importance of smoking bans and health behaviour interventions at the individual level in developing an anti-smoking attitude.",
keywords = "Environmental exposure, Genetics, Heritability, Smoking habits, Tobacco smoking",
author = "Tarnoki, {David Laszlo} and Tarnoki, {Adam Domonkos} and Levente Littvay and Zsofia Lazar and Kinga Karlinger and Molnar, {Andrea Agnes} and Dora Melicher and Zsolt Garami and Viktor Berczi and Ildiko Horvath",
year = "2014",
month = "1",
day = "1",
doi = "10.5604/12321966.1129931",
language = "English (US)",
volume = "21",
pages = "771--775",
journal = "Annals of Agricultural and Environmental Medicine",
issn = "1232-1966",
publisher = "Institute of Agricultural Medicine",
number = "4",

}

RIS

TY - JOUR

T1 - Transmission of second-hand smoke sensitivity and smoking attitude in a family

AU - Tarnoki, David Laszlo

AU - Tarnoki, Adam Domonkos

AU - Littvay, Levente

AU - Lazar, Zsofia

AU - Karlinger, Kinga

AU - Molnar, Andrea Agnes

AU - Melicher, Dora

AU - Garami, Zsolt

AU - Berczi, Viktor

AU - Horvath, Ildiko

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Introduction and objective. The role of genetic factors in nicotine dependence is well understood, but no information is available on the inheritability of second-hand smoke (SHS) exposure sensitivity and their co-variance.Materials and methods. 186 adult same-gender pairs of twin (146 monozygotic, 40 dizygotic; 44±17 years±SD) completed a questionnaire.Results. The model showed a significant role of unshared environmental factors influencing the co-variance between smoking habit and SHS sensitivity (re=-0.191, 95% CI, -0.316 to -0.056, or the total phenotypic correlation of rph=-0.406, p<0.001) without evidence for genetic covariation. Age, gender and country-adjusted analysis indicated 51.5% heritability for smoking habit (95% confidence interval/CI/, 6.2 to 89.8%), 49.7% for SHS sensitivity (95%CI, 19.1–72.0%), 35.5% for general opinions on SHS exposure in restaurants/cafés (95%CI, 10.7–58.6%), and 16.9% in pubs/bars (95%CI, 0.0–49.0%).Conclusions. The co-variance between SHS sensitivity and smoking habits is driven mainly by the unshared environment. SHS sensitivity is moderately inheritable. The considerable influence of environmental factors on general opinions on SHS exposure in designated indoor public venues emphasizes the importance of smoking bans and health behaviour interventions at the individual level in developing an anti-smoking attitude.

AB - Introduction and objective. The role of genetic factors in nicotine dependence is well understood, but no information is available on the inheritability of second-hand smoke (SHS) exposure sensitivity and their co-variance.Materials and methods. 186 adult same-gender pairs of twin (146 monozygotic, 40 dizygotic; 44±17 years±SD) completed a questionnaire.Results. The model showed a significant role of unshared environmental factors influencing the co-variance between smoking habit and SHS sensitivity (re=-0.191, 95% CI, -0.316 to -0.056, or the total phenotypic correlation of rph=-0.406, p<0.001) without evidence for genetic covariation. Age, gender and country-adjusted analysis indicated 51.5% heritability for smoking habit (95% confidence interval/CI/, 6.2 to 89.8%), 49.7% for SHS sensitivity (95%CI, 19.1–72.0%), 35.5% for general opinions on SHS exposure in restaurants/cafés (95%CI, 10.7–58.6%), and 16.9% in pubs/bars (95%CI, 0.0–49.0%).Conclusions. The co-variance between SHS sensitivity and smoking habits is driven mainly by the unshared environment. SHS sensitivity is moderately inheritable. The considerable influence of environmental factors on general opinions on SHS exposure in designated indoor public venues emphasizes the importance of smoking bans and health behaviour interventions at the individual level in developing an anti-smoking attitude.

KW - Environmental exposure

KW - Genetics

KW - Heritability

KW - Smoking habits

KW - Tobacco smoking

UR - http://www.scopus.com/inward/record.url?scp=84915815356&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84915815356&partnerID=8YFLogxK

U2 - 10.5604/12321966.1129931

DO - 10.5604/12321966.1129931

M3 - Article

VL - 21

SP - 771

EP - 775

JO - Annals of Agricultural and Environmental Medicine

T2 - Annals of Agricultural and Environmental Medicine

JF - Annals of Agricultural and Environmental Medicine

SN - 1232-1966

IS - 4

ER -

ID: 6654640