Transitional Cell Carcinoma Metastatic to Lung, With Dedifferentiation Into Small Cell Undifferentiated Carcinoma

David L. Todd; Rodolfo Laucirica; Mary L. Ostrowski; Richard Brown; Luan Truong

doi:10.1177/106689699400200211

Transitional Cell Carcinoma Metastatic to Lung, With Dedifferentiation Into Small Cell Undifferentiated Carcinoma

David L. Todd, Rodolfo Laucirica, Mary L. Ostrowski, Richard Brown, Luan Truong

Research output: Contribution to journal › Article › peer-review

Abstract

Small-cell undifferentiated carcinoma (SCUC) has been increasingly recognized in the urinary tract.^1,2,3 Up to 66% of SCUCs in this location are associated with a minor component of a more differentiated carcinoma that most frequently represents transi tional-cell carcinoma (TCC), but adenocarcinoma, squamous-cell carcinoma, spindle- cell carcinoma, and carcinoid carcinoma have all been described. We report a case of low-grade TCC of the urinary tract metastasizing to a distant location and therein dedifferentiating into an SCUC and discuss the clinical and biologic implication of the process of dedifferentiation. Int J Surg Pathol 2(2):157-162, 1994

Original language	English (US)
Pages (from-to)	157-162
Number of pages	6
Journal	International Journal of Surgical Pathology
Volume	2
Issue number	2
DOIs	https://doi.org/10.1177/106689699400200211
State	Published - 1994

Keywords

dedif ferentiation
small-cell undifferentiated carcinoma
transitional cell carcinoma

ASJC Scopus subject areas

Anatomy
Surgery
Pathology and Forensic Medicine

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10.1177/106689699400200211

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title = "Transitional Cell Carcinoma Metastatic to Lung, With Dedifferentiation Into Small Cell Undifferentiated Carcinoma",

abstract = "Small-cell undifferentiated carcinoma (SCUC) has been increasingly recognized in the urinary tract.1,2,3 Up to 66\% of SCUCs in this location are associated with a minor component of a more differentiated carcinoma that most frequently represents transi tional-cell carcinoma (TCC), but adenocarcinoma, squamous-cell carcinoma, spindle- cell carcinoma, and carcinoid carcinoma have all been described. We report a case of low-grade TCC of the urinary tract metastasizing to a distant location and therein dedifferentiating into an SCUC and discuss the clinical and biologic implication of the process of dedifferentiation. Int J Surg Pathol 2(2):157-162, 1994",

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author = "Todd, \{David L.\} and Rodolfo Laucirica and Ostrowski, \{Mary L.\} and Richard Brown and Luan Truong",

year = "1994",

doi = "10.1177/106689699400200211",

language = "English (US)",

volume = "2",

pages = "157--162",

journal = "International Journal of Surgical Pathology",

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TY - JOUR

T1 - Transitional Cell Carcinoma Metastatic to Lung, With Dedifferentiation Into Small Cell Undifferentiated Carcinoma

AU - Todd, David L.

AU - Laucirica, Rodolfo

AU - Ostrowski, Mary L.

AU - Brown, Richard

AU - Truong, Luan

PY - 1994

Y1 - 1994

N2 - Small-cell undifferentiated carcinoma (SCUC) has been increasingly recognized in the urinary tract.1,2,3 Up to 66% of SCUCs in this location are associated with a minor component of a more differentiated carcinoma that most frequently represents transi tional-cell carcinoma (TCC), but adenocarcinoma, squamous-cell carcinoma, spindle- cell carcinoma, and carcinoid carcinoma have all been described. We report a case of low-grade TCC of the urinary tract metastasizing to a distant location and therein dedifferentiating into an SCUC and discuss the clinical and biologic implication of the process of dedifferentiation. Int J Surg Pathol 2(2):157-162, 1994

AB - Small-cell undifferentiated carcinoma (SCUC) has been increasingly recognized in the urinary tract.1,2,3 Up to 66% of SCUCs in this location are associated with a minor component of a more differentiated carcinoma that most frequently represents transi tional-cell carcinoma (TCC), but adenocarcinoma, squamous-cell carcinoma, spindle- cell carcinoma, and carcinoid carcinoma have all been described. We report a case of low-grade TCC of the urinary tract metastasizing to a distant location and therein dedifferentiating into an SCUC and discuss the clinical and biologic implication of the process of dedifferentiation. Int J Surg Pathol 2(2):157-162, 1994

KW - dedif ferentiation

KW - small-cell undifferentiated carcinoma

KW - transitional cell carcinoma

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Transitional Cell Carcinoma Metastatic to Lung, With Dedifferentiation Into Small Cell Undifferentiated Carcinoma

Abstract

Keywords

ASJC Scopus subject areas

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