Transient dyslipidemia mimicking the plasma lipid profile of Tangier disease in a diabetic patient with gram negative sepsis

Carlos Palacio, Irene Alexandraki, Roger L. Bertholf, Arshag D. Mooradian

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Tangier disease is a rare genetic disorder of lipid metabolism characterized by low concentrations of plasma high density lipoprotein (HDL) and low density lipoprotein (LDL) cholesterol with normal or elevated levels of triglycerides. In this case report we desceribe a patient with diabetes who experienced an episode of urosepsis with a plasma lipid profile resembling Tangier disease. Experimental evidence in the literature suggests that similar lipid changes may occur due to cytokines released during sepsis. Clinicians should be aware of these changes to avoid misdiagnosis of lipid disorders.

Original languageEnglish (US)
Pages (from-to)150-153
Number of pages4
JournalAnnals of clinical and laboratory science
Volume41
Issue number2
StatePublished - Mar 1 2011

ASJC Scopus subject areas

  • Microbiology
  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology
  • Molecular Biology
  • Hematology
  • Clinical Biochemistry
  • Medical Laboratory Technology

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