Biopsies from volunteers challenged with Cryptosporidium parvum were examined for transforming growth factor β1 (TGF-β1). None of the prechallenge biopsies exhibited TGF-β. Seven of 12 volunteers with oocyst shedding expressed TGF-β versus 2 of 13 volunteers without detected oocysts. The association of TGF-β expression with oocyst excretion and the timing of symptoms suggests that TGF-β mediates intestinal healing.
|Original language||English (US)|
|Number of pages||3|
|Journal||Infection and Immunity|
|State||Published - 2000|
ASJC Scopus subject areas
- Infectious Diseases