Transcatheter Management of Tricuspid Regurgitation: A Review of Contemporary Evidence

Tricuspid regurgitation (TR) is a common valvular heart disease that is associated with increased morbidity and mortality. Traditional surgical interventions, though definitive, carry considerable complexities and risks, especially for high-risk patients, with in-hospital mortality rates of ~9%. This resulted in the undertreatment of many patients with TR, creating a substantial unmet need. This has stimulated the development of transcatheter techniques, such as transcatheter tricuspid valve replacement, tricuspid edge-to-edge repair, tricuspid annuloplasty, caval valve implantation and many others, which offer less-invasive alternatives with promising early results and sustained benefits. This review provides a contemporary outlook on different transcatheter tricuspid valve interventions in patients with severe TR and assesses the existing clinical data regarding the safety and effectiveness of these devices in a rapidly expanding space.